Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 12800
TargetAdenosine receptor A2b(Human)
Leadxpro

US Patent
LigandPNGBDBM729456(Preparation of 5-Cyclobutyl-N-[4-(2-Fluorophenyl)-...)
Affinity DataEC50:  2.20nMAssay Description:In all radioligand binding experiments, the samples were incubated in a final volume of 0.1 ml of binding buffer for 60 minutes at 25° C. and then fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Leadxpro

US Patent
LigandPNGBDBM729456(Preparation of 5-Cyclobutyl-N-[4-(2-Fluorophenyl)-...)
Affinity DataEC50: <5nMAssay Description:In all radioligand binding experiments, the samples were incubated in a final volume of 0.1 ml of binding buffer for 60 minutes at 25° C. and then fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Leadxpro

US Patent
LigandPNGBDBM729456(Preparation of 5-Cyclobutyl-N-[4-(2-Fluorophenyl)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:In all radioligand binding experiments, the samples were incubated in a final volume of 0.1 ml of binding buffer for 60 minutes at 25° C. and then fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Leadxpro

US Patent
LigandPNGBDBM729456(Preparation of 5-Cyclobutyl-N-[4-(2-Fluorophenyl)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:In all radioligand binding experiments, the samples were incubated in a final volume of 0.1 ml of binding buffer for 60 minutes at 25° C. and then fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent