Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 12814
Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730297(US20250109139, Compound I-A43)
Affinity DataKi:  0.0150nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730292(US20250109139, Compound I-A22)
Affinity DataKi:  0.0730nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730296(US20250109139, Compound I-A42)
Affinity DataKi:  0.420nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730293(US20250109139, Compound I-A27)
Affinity DataKi:  0.640nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730295(US20250109139, Compound I-A41)
Affinity DataKi:  0.780nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730294(US20250109139, Compound I-A32)
Affinity DataKi:  2.55nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730284(US20250109139, Compound I-B7)
Affinity DataKi:  2.71nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730267(US20250109139, Compound I-A15)
Affinity DataKi:  5.43nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50443101(Cariprazine | RGH-188 | US20250109139, Compound Ca...)
Affinity DataKi:  9.94nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730268(US20250109139, Compound I-A16)
Affinity DataKi:  16.5nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730291(US20250109139, Compound I-D6)
Affinity DataKi:  16.8nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730286(US20250109139, Compound I-B10)
Affinity DataKi:  23.2nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730275(US20250109139, Compound I-A29)
Affinity DataKi:  27.7nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730273(US20250109139, Compound I-A25)
Affinity DataKi:  38nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  42.2nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  53.8nMAssay Description:Table 3: In the first step, a cell membrane component containing specific 5-HT1A receptors was prepared. A 10 cm culture dish with HEK-293T cells was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50443101(Cariprazine | RGH-188 | US20250109139, Compound Ca...)
Affinity DataKi:  62.9nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730280(US20250109139, Compound I-B2)
Affinity DataKi:  78.9nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  84.4nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730269(US20250109139, Compound I-A18)
Affinity DataKi:  88.8nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730271(US20250109139, Compound I-A20)
Affinity DataKi:  89.5nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730274(US20250109139, Compound I-A28)
Affinity DataKi:  103nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  113nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730263(US20250109139, Compound I-A10)
Affinity DataKi:  139nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50633018(CHEMBL5427288 | US20250109139, Compound I-A8)
Affinity DataKi:  149nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730276(US20250109139, Compound I-A30)
Affinity DataKi:  151nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50633017(CHEMBL5433201 | US20250109139, Compound I-A9)
Affinity DataKi:  204nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730288(US20250109139, Compound I-C2)
Affinity DataKi:  221nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730290(US20250109139, Compound I-C8)
Affinity DataKi:  239nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730283(US20250109139, Compound I-B6)
Affinity DataKi:  266nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730267(US20250109139, Compound I-A15)
Affinity DataKi:  272nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730281(US20250109139, Compound I-B3)
Affinity DataKi:  282nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50633014(CHEMBL5393856 | US20250109139, Compound I-A5)
Affinity DataKi:  290nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730279(US20250109139, Compound I-B1)
Affinity DataKi:  362nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730285(US20250109139, Compound I-B8)
Affinity DataKi:  381nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730287(US20250109139, Compound I-C1)
Affinity DataKi:  401nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730264(US20250109139, Compound I-A12)
Affinity DataKi:  436nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730289(US20250109139, Compound I-C5)
Affinity DataKi:  438nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730272(US20250109139, Compound I-A21)
Affinity DataKi:  524nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730277(US20250109139, Compound I-A34)
Affinity DataKi:  605nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730278(US20250109139, Compound I-A45)
Affinity DataKi:  714nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730282(US20250109139, Compound I-B4)
Affinity DataKi:  728nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730266(US20250109139, Compound I-A14)
Affinity DataKi:  752nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730270(US20250109139, Compound I-A19)
Affinity DataKi:  930nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50633011(CHEMBL5409419 | US20250109139, Compound I-A2)
Affinity DataKi:  1.11E+3nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730271(US20250109139, Compound I-A20)
Affinity DataKi:  1.31E+3nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730268(US20250109139, Compound I-A16)
Affinity DataKi:  1.32E+3nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730265(US20250109139, Compound I-A13)
Affinity DataKi:  1.72E+3nMAssay Description:Table 1: In the first step, a cell membrane component containing specific dopamine D2 receptors was prepared. A 10 cm culture dish was used for trans...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM50633010(CHEMBL5426242 | US20250109139, Compound I-A1)
Affinity DataKi:  1.79E+3nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM730284(US20250109139, Compound I-B7)
Affinity DataKi:  3.51E+3nMAssay Description:Table 5: The affinity of the compounds of the present disclosure for 5-HT2A receptors was determined by a radioligand competition binding assay. In t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

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