Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 12842
TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732865(2-(4,4-difluoroazepan-1-yl)-6,7-difluoro-N-(3-sulf...)
Affinity DataIC50: 0.0710nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732865(2-(4,4-difluoroazepan-1-yl)-6,7-difluoro-N-(3-sulf...)
Affinity DataIC50: 0.0840nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732866(2-(4,4-difluoroazepan-1-yl)-6,7-difluoro-N-(2-sulf...)
Affinity DataIC50: 0.0950nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732864(2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridine...)
Affinity DataIC50: 0.340nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732867(N-(3-carbamoyl-4-fluorophenyl)-2-(4,4-difluoroazep...)
Affinity DataIC50: 0.360nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732863(N-(2-carbamoylpyridin-4-yl)-2-(4,4-difluoroazepan-...)
Affinity DataIC50: 0.460nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732864(2-(4,4-difluoroazepan-1-yl)-N-(2-sulfamoylpyridine...)
Affinity DataIC50: 0.725nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732863(N-(2-carbamoylpyridin-4-yl)-2-(4,4-difluoroazepan-...)
Affinity DataIC50: 0.784nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732862(US20250115578, KH09 | US20250115578, Example 09)
Affinity DataIC50: 0.918nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732862(US20250115578, KH09 | US20250115578, Example 09)
Affinity DataIC50: 1nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732869(N-(2-carbamoylpyridin-4-yl)-2-(4,4-difluoroazepan-...)
Affinity DataIC50: 1.5nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732861(US20250115578, KH08 | US20250115578, Example 08)
Affinity DataIC50: 1.74nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732854(US20250115578, KH02 | US20250115578, Example 02)
Affinity DataIC50: 2.82nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732859(US20250115578, KH06 | US20250115578, Example 06)
Affinity DataIC50: 3.10nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732861(US20250115578, KH08 | US20250115578, Example 08)
Affinity DataIC50: 3.30nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732854(US20250115578, KH02 | US20250115578, Example 02)
Affinity DataIC50: 5.30nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732872(2-(4,4-difluoroazepan-1-yl)-N-(2-(S-methylsulfonim...)
Affinity DataIC50: 8nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732858(US20250115578, KH05 | US20250115578, Example 05)
Affinity DataIC50: 8.90nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732871(N-(2-carbamoylpyridin-4-yl)-2-(4,4-difluoroazepan-...)
Affinity DataIC50: 9.23nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM181223(US9139529, 66 | US9783501, Compound 66 | US2025011...)
Affinity DataIC50: 9.5nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732855(US20250115578, KH03 | US20250115578, Example 03)
Affinity DataIC50: 10nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732873(2-(4,4-difluoroazepan-1-yl)-N-(2-(N-methylsulfamoy...)
Affinity DataIC50: 11.4nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732860(US20250115578, KH07 | US20250115578, Example 07)
Affinity DataIC50: 14.7nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM161225(US9163042, 9a | US9051270, 10 | US10087143, Compou...)
Affinity DataIC50: 16nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732858(US20250115578, KH05 | US20250115578, Example 05)
Affinity DataIC50: 21.3nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM161225(US9163042, 9a | US9051270, 10 | US10087143, Compou...)
Affinity DataIC50: 35.1nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732857(US20250115578, KH04 | US20250115578, Example 04)
Affinity DataIC50: 66.7nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732870(N-(2-carbamoylpyridin-4-yl)-2-(4,4-difluoroazepan-...)
Affinity DataIC50: 97.1nMAssay Description:Clamped the cell at −80 mV and then depolarized to 10 mV with a square wave lasting 10 ms to get the Nav1.8 current (see FIG. 1 attached). This proce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Chengdu Kanghong Pharmaceutical Co.

US Patent
LigandPNGBDBM732853(US20250115578, KH01 | US20250115578, Example 01)
Affinity DataIC50: 100nMAssay Description:A capillary glass pipette (BF150-86-10, Sutter Instruments) was pulled into a recording electrode with a micropipette puller (P97, Sutter Instruments...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent