Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 12862
TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734330(US20250129055, Compound 2)
Affinity DataIC50: 0.105nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM50448927(CHEMBL3125318 | US20250129055, Control Dapaglifloz...)
Affinity DataIC50: 0.147nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734429(US20250129055, Compound 8)
Affinity DataIC50: 0.356nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734431(US20250129055, Compound 12)
Affinity DataIC50: 1.01nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734432(US20250129055, Compound 24)
Affinity DataIC50: 1.36nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734428(US20250129055, Compound 5)
Affinity DataIC50: 2.26nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734433(US20250129055, Compound 27)
Affinity DataIC50: 3.32nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734430(US20250129055, Compound 11)
Affinity DataIC50: 3.52nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetSodium/glucose cotransporter 2(Human)
Beijing Increase Innovative Drug Co.

US Patent
LigandPNGBDBM734427(US20250129055, Compound 3)
Affinity DataIC50: 6.75nMAssay Description:1. Materials and methods(1) MaterialsThe humanized SGLT2 overexpression cells (CHO-SGLT2) constructed from Chinese hamster ovary (CHO) cells were cul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent