Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 12866
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50233225(CHEMBL4071864 | US12065447, Compound GSK2982772 | ...)
Affinity DataIC50: 32nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50599964(CHEMBL5179059 | US20250129073, Compound 49)
Affinity DataIC50: 92nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM734988(US20250129073, Compound 50)
Affinity DataIC50: 102nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM734985(US20250129073, Compound 44)
Affinity DataIC50: 186nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50599961(CHEMBL5198841 | US20250129073, Compound 31)
Affinity DataIC50: 186nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50599963(CHEMBL5177216 | US20250129073, Compound 46)
Affinity DataIC50: 624nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM50599962(CHEMBL5187835 | US20250129073, Compound 34)
Affinity DataIC50: 693nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM734984(US20250129073, Compound 42)
Affinity DataIC50: 1.04E+3nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
China Pharmaceutical University

US Patent
LigandPNGBDBM36371(CID2828334 | 5-(1H-indol-3-ylmethyl)-3-methyl-2-th...)
Affinity DataIC50: 1.14E+3nMAssay Description:The compounds were diluted in DMSO and configured into a solution with a final concentration of 10 mM; Dilute RIP1 kinase from 140 ng/μL to 20 ng/μL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2025
Entry Details
US Patent