Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 12884
Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737421(US20250136601, Compound I-15)
Affinity DataKi:  7nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737433(Preparation of (8aR,12aS)-11-(3-(2-methoxyphenyl)p...)
Affinity DataKi:  8nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737429(Preparation of (6bS,10aR)-8-(3-(2-methoxyphenyl)pr...)
Affinity DataKi:  11nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737416(Preparation of (6bR,10aS)-8-(3-(2-methoxy)propyl)-...)
Affinity DataKi:  13nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737409(Preparation of (6bR,10aS)-8-(2-methoxyphenyl)-3-me...)
Affinity DataKi:  17nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737425(Preparation of (7aR,11aS)-10-(3-(2-methoxyphenyl)p...)
Affinity DataKi:  18nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737423(Preparation of (7aR,11aS)-10-(2-methoxyphenethyl)-...)
Affinity DataKi:  24nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737420(US20250136601, Compound I-14)
Affinity DataKi:  28nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737415(Preparation of 2-(2-((6bR,10aS)-3-methyl-2,3,6b,9,...)
Affinity DataKi:  31nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737431(Preparation of (8aR,12aS)-11-(2-methoxyphenethyl)-...)
Affinity DataKi:  32nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737419(US20250136601, Compound I-13)
Affinity DataKi:  34nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737427(Preparation of (6bS,10aR)-8-(2-methoxyphenethyl)-1...)
Affinity DataKi:  43nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737430(Preparation of (8aS,12aR)-11-(2-methoxyphenethyl)-...)
Affinity DataKi:  45nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737424(Preparation of 10-(3-(2-methoxyphenyl)propyl)-5,6,...)
Affinity DataKi:  57nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737422(Preparation of (7aS,11aR)-10-(2-methoxyphenethyl)-...)
Affinity DataKi:  65nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737410(Preparation of (6bR,10aS)-8-(3-methoxyphenyl)-3-me...)
Affinity DataKi:  88nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737417(Preparation of 2-(3-((6bR,10aS)-3-methyl-2,3,6b,9,...)
Affinity DataKi:  89nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737432(Preparation of (8aS,12aR)-11-(3-(2-methoxyphenyl)p...)
Affinity DataKi:  93nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737428(Preparation of (6bR,10aS)-8-(3-(2-methoxyphenyl)pr...)
Affinity DataKi:  99nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737426(Preparation of (6bR,10aS)-8-(2-methoxyphenethyl)-1...)
Affinity DataKi:  107nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737411(Preparation of (6bR,10aS)-8-(4-methoxyphenyl)-3-me...)
Affinity DataKi:  126nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737418(US20250136601, Compound I-12)
Affinity DataKi:  190nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737407(Preparation of (6bR,10aS)-8-(2-methoxyphenyl)-3-me...)
Affinity DataKi:  246nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737408(Preparation of 2-(((6bR,10aS)-3-methyl-2,3,6b,9,10...)
Affinity DataKi:  525nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737413(Preparation of (6bR,10aS)-8-(2,4-methoxyphenyl)-3-...)
Affinity DataKi:  1.58E+3nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737414(Preparation of (6bR,10aS)-8-(2,5-dimethoxy)-3-meth...)
Affinity DataKi:  3.06E+3nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Shanghaitech University

US Patent
LigandPNGBDBM737412(Preparation of (6bR,10aS)-8-(2,3-dimethoxyphenyl)-...)
Affinity DataKi:  5.25E+3nMAssay Description:Method: The affinity of the compounds of the present disclosure for the 5-HT2A receptor was determined using a radioligand competitive binding assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2025
Entry Details
US Patent