Compile Data Set for Download or QSAR
Report error Found 365 Enz. Inhib. hit(s) with all data for entry = 12933
TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741390(US20250162989, Compound I-177)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741389(US20250162989, Compound I-175)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741351(US20250162989, Compound I-112)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741387(US20250162989, Compound I-173)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741386(US20250162989, Compound I-172)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741569(US20250162989, Compound I-238)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741385(US20250162989, Compound I-171)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741384(US20250162989, Compound I-168)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741582(US20250162989, Compound I-251)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741398(US20250162989, Compound I-202)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741354(US20250162989, Compound I-121)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741581(US20250162989, Compound I-250)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741397(US20250162989, Compound I-201)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741580(US20250162989, Compound I-249)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741396(US20250162989, Compound I-200)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741394(US20250162989, Compound I-196)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741353(US20250162989, Compound I-117)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741499(US20250162989, Compound I-116)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741392(US20250162989, Compound I-185)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741352(US20250162989, Compound I-115)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741391(US20250162989, Compound I-182)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741374(US20250162989, Compound I-156)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741373(US20250162989, Compound I-155)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741372(US20250162989, Compound I-151)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741371(US20250162989, Compound I-150)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741370(US20250162989, Compound I-149)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741368(US20250162989, Compound I-145)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741382(US20250162989, Compound I-165)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741381(US20250162989, Compound I-164)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741380(US20250162989, Compound I-163)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741379(US20250162989, Compound I-161)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741344(US20250162989, Compound I-101)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741378(US20250162989, Compound I-160)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741376(US20250162989, Compound I-158)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741342(US20250162989, Compound I-97)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741368(US20250162989, Compound I-145)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741418(US20250162989, Compound I-11)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741415(US20250162989, Compound I-8)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741423(US20250162989, Compound I-16)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741505(US20250162989, Compound I-126)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741413(US20250162989, Compound I-6)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741411(US20250162989, Compound I-4)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741409(US20250162989, Compound I-2)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741408(US20250162989, Compound I-1)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741407(US20250162989, Compound I-293)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741360(US20250162989, Compound I-131)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741407(US20250162989, Compound I-293)
Affinity DataIC50: 50nMAssay Description:USP30 (25 ng/μl) tested against K48-linked diubiquitin (5.6 μM). USP30 was diluted in a buffer containing 40 mM Tris, 0.01% BSA, 1 mM DTT and K48 in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741359(US20250162989, Compound I-130)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741390(US20250162989, Compound I-177)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Vincere Biosciences

US Patent
LigandPNGBDBM741389(US20250162989, Compound I-175)
Affinity DataIC50: 50nMAssay Description:In vitro biochemical assay to establish the potency of compounds for USP30 inhibition: a 384-well plate assay using a fluorophore tagged substrate of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/19/2025
Entry Details
US Patent

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