Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 12957
LigandPNGBDBM744654((5S)-6-[4-(cyclopentylamino)-3-(trifluoromethyl)ph...)
Affinity DataIC50: 1nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744653((5S)-6-[4-(3-hydroxy-3-methylazetidin-1-yl)-3-(tri...)
Affinity DataIC50: 1nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744654((5S)-6-[4-(cyclopentylamino)-3-(trifluoromethyl)ph...)
Affinity DataIC50: 2nMAssay Description:For the determination of the in vitro effect of example compounds on the PDE3A reactions 2 μl of the respective example compound solution in DMSO (se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744653((5S)-6-[4-(3-hydroxy-3-methylazetidin-1-yl)-3-(tri...)
Affinity DataIC50: 2nMAssay Description:For the determination of the in vitro effect of example compounds on the PDE3A reactions 2 μl of the respective example compound solution in DMSO (se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744656((5S)-5-methyl-6-[4-{[(pyrazin-2-yl)methyl]amino}-3...)
Affinity DataIC50: 4nMAssay Description:For the determination of the in vitro effect of example compounds on the PDE3A reactions 2 μl of the respective example compound solution in DMSO (se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744655((5S)-5-methyl-6-[4-{[(2R)-3,3,3-trifluoro-2-hydrox...)
Affinity DataIC50: 4nMAssay Description:For the determination of the in vitro effect of example compounds on the PDE3A reactions 2 μl of the respective example compound solution in DMSO (se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744656((5S)-5-methyl-6-[4-{[(pyrazin-2-yl)methyl]amino}-3...)
Affinity DataIC50: 5nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744655((5S)-5-methyl-6-[4-{[(2R)-3,3,3-trifluoro-2-hydrox...)
Affinity DataIC50: 5nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744652((5S)-5-methyl-6-[4-{[(1H-pyrazol-5-yl)methyl]amino...)
Affinity DataIC50: 5nMAssay Description:For the determination of the in vitro effect of example compounds on the PDE3A reactions 2 μl of the respective example compound solution in DMSO (se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744652((5S)-5-methyl-6-[4-{[(1H-pyrazol-5-yl)methyl]amino...)
Affinity DataIC50: 6nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744651((5S)-5-methyl-6-{3-(trifluoromethyl)-4-[3-(trifluo...)
Affinity DataIC50: 81nMAssay Description:The commercially available 3H-cAMP Scintillation Proximity Assay (SPA, Perkin Elmer) system was used for enzyme inhibition studies. For the determina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM744651((5S)-5-methyl-6-{3-(trifluoromethyl)-4-[3-(trifluo...)
Affinity DataIC50: 91nMAssay Description:For the determination of the in vitro effect of example compounds on the PDE3A reactions 2 μl of the respective example compound solution in DMSO (se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent