Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 12959
TargetProthrombin(Human)TBA
LigandPNGBDBM744714((2S)-N-(2-amino-6,7-dihydro-5H-cyclopenta[b]pyridi...)
Affinity DataIC50: 1.01E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProthrombin(Human)TBA
LigandPNGBDBM744713((2S)-N-(2-amino-6,7-dihydro-5H-cyclopenta[b]pyridi...)
Affinity DataIC50: 1.03E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProthrombin(Human)TBA
LigandPNGBDBM744711((2S)-1-(2R,4S)-4-([1,1'-biphenyl]-4-(4-methyl) pyr...)
Affinity DataIC50: 1.19E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProthrombin(Human)TBA
LigandPNGBDBM744712((2S)-1-(2R,4S)-4-([1,1'-biphenyl]-4-(4-ylmethyl) p...)
Affinity DataIC50: 1.66E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProthrombin(Human)TBA
LigandPNGBDBM744715((2R,4S)-N-((S)-1-(((R)-2-amino-6,7-dihydro-5H-cycl...)
Affinity DataIC50: 2.75E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProthrombin(Human)TBA
LigandPNGBDBM744710((2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-N-((2S)-1-(...)
Affinity DataIC50: 5.00E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetProthrombin(Human)TBA
LigandPNGBDBM744709((2R,4S)-N-((2S)-1-((2-amino-6,7-dihydro-5H-cyclope...)
Affinity DataIC50: 5.00E+4nMAssay Description:For thrombin assay, a fluorescent peptide substrate (Boc-VPR-AMC (R&D Systems)) was used and reacted in a buffer containing 20 mM Hepes (pH 7.4), 140...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent