Compile Data Set for Download or QSAR
Report error Found 227 Enz. Inhib. hit(s) with all data for entry = 13057
TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755720(US20250214942, Example 199)
Affinity DataIC50: 8.30nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755701(1-((3-(5-(5-cyanopyridin-3- yl)-4,5-dihydro-1H-pyr...)
Affinity DataIC50: 9.10nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755723(1-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyr...)
Affinity DataIC50: 9.40nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755707(1-((3-(5-(3-fluorophenyl)- 4,5-dihydro-1H-pyrazole...)
Affinity DataIC50: 9.60nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755592(1-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyra...)
Affinity DataIC50: 10nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755610(3-(1-(3-((4-fluoro-1H- indazol-1-yl)methyl)bicyclo...)
Affinity DataIC50: 11nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755593((3-((1H-pyrazolo[4,3-b]- pyridin-1-yl)methyl)bicyc...)
Affinity DataIC50: 11nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755609((3-((4-fluoro-1H-indazol-1- yl)methyl)bicyclo[1.1....)
Affinity DataIC50: 11nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755747((3-((4-bromo-2-chloro- phenoxy)methyl)bicyclo- [...)
Affinity DataIC50: 11nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755550(US20250214942, Example 22)
Affinity DataIC50: 11nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755724(1-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyr...)
Affinity DataIC50: 11nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755542(US20250214942, Example 14)
Affinity DataIC50: 12nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755748((3-((4-bromo-2-fluoro- phenoxy)methyl)bicyclo- [...)
Affinity DataIC50: 13nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755555(US20250214942, Example 27)
Affinity DataIC50: 14nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755594(1-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyra...)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755578(US20250214942, Example 50)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755703(1-((3-(5-(3-cyanophenyl)-4,5- dihydro-1H-pyrazole-...)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755750(4-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyr...)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755537(US20250214942, Example 9)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755611((3-((4-fluoro-1H-indazol-1- yl)methyl)bicyclo[1.1....)
Affinity DataIC50: 16nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755656(1-((3-(5-(5-fluoropyridin-3- yl)-4,5-dihydro-1H-py...)
Affinity DataIC50: 17nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755533(US20250214942, Example 5)
Affinity DataIC50: 17nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755752((3-((2,4-difluorophenoxy)- methyl)bicyclo[1.1.1]p...)
Affinity DataIC50: 18nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755751((3-((2-chloro-4-fluoro- phenoxy)methyl)bicyclo- ...)
Affinity DataIC50: 18nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755663((3-((1H-pyrazolo[3,4-b]- pyrazin-1-yl)methyl)- bic...)
Affinity DataIC50: 18nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755742((5-(3,5-difluorophenyl)-4,5- dihydro-1H-pyrazol-1...)
Affinity DataIC50: 18nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755613((5-(3,5-difluorophenyl)-4,5- dihydro-1H-pyrazol-1-...)
Affinity DataIC50: 18nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755704(1-((3-(4-fluoro-2-(3-fluoro- phenyl)pyrrolidine-1-...)
Affinity DataIC50: 19nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755749((3-((2-chloro-3-fluoro- phenoxy)methyl)bicyclo- ...)
Affinity DataIC50: 19nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755584(2-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyra...)
Affinity DataIC50: 19nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755614((3-((2H-benzo[d][1,2,3]- triazol-2-yl)methyl)bicyc...)
Affinity DataIC50: 19nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755741(6-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyr...)
Affinity DataIC50: 19nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755532(US20250214942, Example 4)
Affinity DataIC50: 19nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755595(1-((3-(5-(3,5-difluorophenyl)- 4,5-dihydro-1H-pyra...)
Affinity DataIC50: 19nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755539(US20250214942, Example 11)
Affinity DataIC50: 20nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755664((3-((7H-pyrrolo[2,3-d]- pyrimidin-7-yl)methyl)- bi...)
Affinity DataIC50: 20nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755661((5-(3,5-difluorophenyl)-4,5- dihydro-1H-pyrazol-1-...)
Affinity DataIC50: 20nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755596((3-((7-chloro-1H-pyrazolo- [4,3-c]pyridin-1-yl)met...)
Affinity DataIC50: 20nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755535(US20250214942, Example 7)
Affinity DataIC50: 21nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755615((3-((1H-pyrazolo[3,4-c]- pyridin-1-yl)methyl)bicyc...)
Affinity DataIC50: 21nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755743((5-(3,5-difluorophenyl)-4,5- dihydro-1H-pyrazol-1...)
Affinity DataIC50: 21nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755577(US20250214942, Example 49)
Affinity DataIC50: 22nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755543(US20250214942, Example 15)
Affinity DataIC50: 22nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755597((3-((7-chloro-1H-indazol-1- yl)methyl)bicyclo[1.1....)
Affinity DataIC50: 22nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755612((5-(2,5-difluorophenyl)-4,5- dihydro-1H-pyrazol-1-...)
Affinity DataIC50: 22nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755579(US20250214942, Example 51)
Affinity DataIC50: 22nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755734(1-((3-(2-(2-fluorophenyl)- azetidine-1-carbonyl)b...)
Affinity DataIC50: 23nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755534(US20250214942, Example 6)
Affinity DataIC50: 23nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755754((5-(3,5-difluorophenyl)-4,5- dihydro-1H-pyrazol-1...)
Affinity DataIC50: 24nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
University ff Texas System

US Patent
LigandPNGBDBM755686((3-((1H-imidazo[1,2-b]- pyrazol-1-yl)methyl)- bicy...)
Affinity DataIC50: 24nMAssay Description:In order to measure RIPK1 activity the ADP-Glo kinase assay (Promega, Catalog #V7002) was used to measure the conversion of ATP to ADP. This enzymati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

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