Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 13086
TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM757084(US20250223270, Example 5A)
Affinity DataIC50: 30nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM477471(US10889555, Example 241 | 5-fluoro-N-((1S,2R)-2-(6...)
Affinity DataIC50: 50nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM477236(US10889555, Example 1 | US11634395, Example 1 | US...)
Affinity DataIC50: 60nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM601204(US11634395, Example 226B | US20250223270, Example ...)
Affinity DataIC50: 60nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM757149(dimethylphenyl)-1-(5-oxo-4,5-dihydro- | US20250223...)
Affinity DataIC50: 70nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM757140(5-chloro-N-((1S,2R)-2-(6-fluoro-2,3- | US202502232...)
Affinity DataIC50: 80nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM757122(5-chloro-N-((1S,2R)-2-(3-chloro-6- | US20250223270...)
Affinity DataIC50: 80nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM601204(US11634395, Example 226B | US20250223270, Example ...)
Affinity DataIC50: 80nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM757086(US20250223270, Example 5B)
Affinity DataIC50: 80nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM601208(US11634395, Example 228B | US20250223270, Example ...)
Affinity DataIC50: 100nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM477471(US10889555, Example 241 | 5-fluoro-N-((1S,2R)-2-(6...)
Affinity DataIC50: 120nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM477309(US10889555, Example 43 | US12344588, Example 2 | U...)
Affinity DataIC50: 140nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM757123(fluoro-2-methylphenyl)-1-(5-oxo-4,5- | US202502232...)
Affinity DataIC50: 140nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM477275(US10889555, Example 11 | 5-chloro-2-(N-((1S,2R)-2-...)
Affinity DataIC50: 180nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM601208(US11634395, Example 228B | US20250223270, Example ...)
Affinity DataIC50: 180nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Human)
Taiho Pharmaceutical Co.

US Patent
LigandPNGBDBM477278(US10889555, Example 14 | 5-chloro-2-(N-((1S,2R)-2-...)
Affinity DataIC50: 250nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent