Compile Data Set for Download or QSAR
Report error Found 558 Enz. Inhib. hit(s) with all data for entry = 13103
TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758634((Racemic) 2'-chloro-5'-methoxy-N-(5- (3-methoxycyc...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758635(2'-chloro-N-(5-((1R or S,3S and R OR 1R and S,3S o...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758664((Racemic) 2'-chloro-N-(6-((4- hydroxyphenyl)amino)...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758665((Racemic) 2'-chloro-5'-methoxy-6- methyl-N-(6-(phe...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758679((Racemic) 4-(5-cyano-2- methoxyphenyl)-6-methyl-N-...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758579(2'-chloro-N-(5-(3- (difluoromethyl)picolinoyl)-5,6...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758580(2'-chloro-N-(5-(5- (difluoromethyl)picolinoyl)-5,6...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758701(4-(5-cyano-2-methoxyphenyl)-N-(5-(N- ethylsulfamoy...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758698(4-(5-cyano-2-methoxyphenyl)-N-(5-(N- isobutylsulfa...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758630(2'-chloro-5'-methoxy-6-methyl-N-(5- (pyrimidine-2-...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758699(N-(5-(N-(tert-butyl)sulfamoyl)-5,6- dihydro-4H-pyr...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758696(4-(5-cyano-2-methoxyphenyl)-N-(5-(N- isopropylsulf...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758704(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(N-(2,2...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758705(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(N-prop...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758702(4-(5-cyano-2-methoxyphenyl)-N-(5-(N- cyclopropylsu...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758703(4-(5-cyano-2-methoxyphenyl)-N-(5-(N- cyclopentylsu...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758716(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-((5-met...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758717(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(morpho...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758714(4-(S-cyano-2-methoxyphenyl)-N-(5- (cyclohexanecarb...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758715(N-(5-(azetidin-1-ylsulfonyl)-5,6- dihydro-4H-pyrro...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758712(4-(5-cyano-2-methoxyphenyl)-N-(5- isonicotinoyl-5,...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758713(4-(5-cyano-2-methoxyphenyl)-N-(5- (cyclopentanecar...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758711(4-(5-cyano-2-methoxyphenyl)-N-(5- (cyclobutanecarb...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758724(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(6-meth...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758725(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(3-meth...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758723(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(S-picolin...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758721(2'-chloro-N-(5-(cyclopropylsulfonyl)- 5,6-dihydro-...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758718(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(piperi...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758719(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(pyrrol...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758733(2'-chloro-5'-methoxy-N-(5-(3-methoxy- 1-methyl-1H-...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758731(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(3-meth...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758728(4-(5-cyano-2-methoxyphenyl)-N-(5- ((1R,2R)-2-metho...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758729(4-(5-cyano-2-methoxyphenyl)-N-(5- ((1s,3s)-3-cyano...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758726(4-(5-cyano-2-methoxyphenyl)-N-(5- ((1s,3s)-3-metho...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758727((Cis and trans) 4-(5-cyano-2- methoxyphenyl)-N-(5-...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758736(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(2-meth...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758734((Cis and trans) 4-(5-cyano-2- methoxyphenyl)-N-(5-...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758735(4-(5-cyano-2-methoxyphenyl)-6- methyl-N-(5-(4-meth...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758748(2'-chloro-N-(5-(3- (difluoromethoxy)azetidine-1-ca...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758747((R)-2'-chloro-N-(5-(3- hydroxypyrrolidine-1-carbon...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758754(2'-chloro-5'-methoxy-6-methyl-N-(5- ((1s,3s)-3- (t...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758755(2'-chloro-5'-methoxy-6-methyl-N-(5- ((1r,3r)-3- (t...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758753(2'-chloro-N-(5-((1s,3s)-3- (difluoromethoxy)cyclob...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758763(2'-chloro-5'-methoxy-6-methyl-N-(5-(5- methyloxazo...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758764(2'-chloro-5'-methoxy-6-methyl-N-(5-(1- methyl-1H-1...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758761(N-(5-(1H-pyrazole-5-carbonyl)-5,6- dihydro-4H-pyrr...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758759(N-(5-(1,2,4-oxadiazole-3-carbonyl)-5,6- dihydro-4H...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758760(2'-chloro-5'-methoxy-6-methyl-N-(5-(4- methyloxazo...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758614(2'-chloro-N-(5-(6- (difluoromethoxy)nicotinoyl)-5,...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

TargetDNA polymerase theta (POLQ) (2-894)(Human)
Moma Therapeutics

US Patent
LigandPNGBDBM758758(2'-chloro-N-(5-(4-chloro-6- (difluoromethyl)nicoti...)
Affinity DataIC50: 8nMAssay Description:POLθ-mediated ATP hydrolysis was measured using the ADP-Glo Kinase Assay (Promega Corporation, Madison, WI). Reactions were performed in white 384-we...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/30/2025
Entry Details
US Patent

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