Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 13149
TargetComplement Factor B/C3(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM762924(US20250250267, Example 1-1)
Affinity DataIC50: 1.30nMAssay Description:Cleavage reactions of the human complement factor B protein: The recombinant human complement factor D protein was diluted 10-fold with PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetComplement Factor B/C3(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM762927(4-((1S,3S,5R)-8-((5-Cyclopropyl-7-methyl-1H-indol-...)
Affinity DataIC50: 1.60nMAssay Description:Cleavage reactions of the human complement factor B protein: The recombinant human complement factor D protein was diluted 10-fold with PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetComplement Factor B/C3(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM762891(US20250250267, Example 1)
Affinity DataIC50: 4.20nMAssay Description:Cleavage reactions of the human complement factor B protein: The recombinant human complement factor D protein was diluted 10-fold with PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetComplement Factor B/C3(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM762926(4-((1S,3S,5R)-8-((5,7-Dimethyl-1H-indol-4-yl)methy...)
Affinity DataIC50: 4.90nMAssay Description:Cleavage reactions of the human complement factor B protein: The recombinant human complement factor D protein was diluted 10-fold with PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetComplement Factor B/C3(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM762928((2S,3S,4S,5R,6S)-6-((4-((1S,3S,5R)-3-Ethoxy-8-((5-...)
Affinity DataIC50: 30nMAssay Description:Cleavage reactions of the human complement factor B protein: The recombinant human complement factor D protein was diluted 10-fold with PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

TargetComplement Factor B/C3(Human)
Jiangsu Hengrui Pharmaceuticals

US Patent
LigandPNGBDBM762925(US20250250267, Example 1-2)
Affinity DataIC50: 72.2nMAssay Description:Cleavage reactions of the human complement factor B protein: The recombinant human complement factor D protein was diluted 10-fold with PBS (pH 7.4) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent