Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 13151
LigandPNGBDBM762967((1S,2S)—N-[(7S,13S)-25-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 9nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762967((1S,2S)—N-[(7S,13S)-25-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 13nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762957(WO2022060836, Compound A122 (page 70 of Table, 1a)...)
Affinity DataIC50: 13nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762967((1S,2S)—N-[(7S,13S)-25-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 20nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762957(WO2022060836, Compound A122 (page 70 of Table, 1a)...)
Affinity DataIC50: 25nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762961((1S,2S)—N-[(7S,13S)-24-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 36nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762966((1S,2S)—N-[(7S,13S)-24-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 90nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762961((1S,2S)—N-[(7S,13S)-24-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 95nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762958((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 108nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762957(WO2022060836, Compound A122 (page 70 of Table, 1a)...)
Affinity DataIC50: 124nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762959((1R,5S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 134nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762965((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 143nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762963(US20250250284, Example 6)
Affinity DataIC50: 154nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762965((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 160nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762966((1S,2S)—N-[(7S,13S)-24-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 171nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762959((1R,5S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 174nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762964((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 192nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762962((1S,2S)-2-cyano-N-[(7S,13S)-21-ethyl-24-fluoro-(20...)
Affinity DataIC50: 194nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762960((1S,2S)-2-(difluoromethyl)-N-[(7S,13S)-21-ethyl-24...)
Affinity DataIC50: 196nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762958((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 211nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762960((1S,2S)-2-(difluoromethyl)-N-[(7S,13S)-21-ethyl-24...)
Affinity DataIC50: 243nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762962((1S,2S)-2-cyano-N-[(7S,13S)-21-ethyl-24-fluoro-(20...)
Affinity DataIC50: 258nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762963(US20250250284, Example 6)
Affinity DataIC50: 273nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762961((1S,2S)—N-[(7S,13S)-24-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 544nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762966((1S,2S)—N-[(7S,13S)-24-fluoro-(20M)-20-[2-[(1S)-1-...)
Affinity DataIC50: 660nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762964((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 697nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762963(US20250250284, Example 6)
Affinity DataIC50: 701nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762962((1S,2S)-2-cyano-N-[(7S,13S)-21-ethyl-24-fluoro-(20...)
Affinity DataIC50: 862nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762958((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 915nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762959((1R,5S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 957nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762965((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 1.67E+3nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762960((1S,2S)-2-(difluoromethyl)-N-[(7S,13S)-21-ethyl-24...)
Affinity DataIC50: 1.72E+3nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent

LigandPNGBDBM762964((1S,2S)—N-[(7S,13S)-21-ethyl-24-fluoro-(20M)-20-[2...)
Affinity DataIC50: 1.00E+4nMAssay Description:In this example, TR-FRET was also used to measure the compound or compound-CYPA dependent disruption of the KRAS G12C-BRAF complex. This protocol was...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/22/2025
Entry Details
US Patent