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Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 13173
TargetTyrosine-protein kinase JAK3(Human)
University of Michigan

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 1.60nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 2nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
University of Michigan

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 3.20nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
University of Michigan

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 4.10nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
University of Michigan

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 10.1nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
University of Michigan

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 15.6nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 16.3nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Michigan

US Patent
LigandPNGBDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 34nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 55.2nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Michigan

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 178nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
University of Michigan

US Patent
LigandPNGBDBM764863(US20250257069, Compound MMT3-72)
Affinity DataIC50: 199nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
University of Michigan

US Patent
LigandPNGBDBM764863(US20250257069, Compound MMT3-72)
Affinity DataIC50: 448nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
University of Michigan

US Patent
LigandPNGBDBM764864(US20250257069, Compound MMT3-72-M2)
Affinity DataIC50: 701nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
University of Michigan

US Patent
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50: 976nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Michigan

US Patent
LigandPNGBDBM764863(US20250257069, Compound MMT3-72)
Affinity DataIC50: 2.98E+3nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
University of Michigan

US Patent
LigandPNGBDBM764863(US20250257069, Compound MMT3-72)
Affinity DataIC50: 6.82E+3nMAssay Description:Biological activities of the MMT3-72 and its active metabolite MMT3-72-M2 were evaluated against JAK1, JAK2, JAK3 and TYK2 using kinase assays (FIG. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent