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Found
38
Enz. Inhib. hit(s) with all data for entry = 13192
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765942
(2,5-dichloro-N- (3-(2-(((1R,4R)-4- (dimethylamino)...)
Copy SMILES
Affinity Data
IC50: 1.11nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765946
(N-(3-(2- (((1R,4R)-4- aminocyclohexyl) amino)quina...)
Copy SMILES
Affinity Data
IC50: 1.64nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765924
((1R,3R)-3-((6-(3- ((2,5-dichloro-3- (hydroxymethyl...)
Copy SMILES
Affinity Data
IC50: 2.12nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765945
(5-chloro-N-(3-(2- (((1R,4R)-4- (dimethylamino)cy- ...)
Copy SMILES
Affinity Data
IC50: 2.35nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765918
(2,5-dichloro-N- (2,4-difluoro-3- (2-(((1R,3R)-3- (...)
Copy SMILES
Affinity Data
IC50: 2.63nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765940
(5-chloro-N-(2,4- difluoro-3-(2- (((1R,4R)-4- (meth...)
Copy SMILES
Affinity Data
IC50: 3.23nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765922
(5-chloro-N-(3-(2- (((1R,4R)-4- (dimethylamino)cy- ...)
Copy SMILES
Affinity Data
IC50: 3.36nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765927
((1R,3R)-3-((6-(3- ((5-chloro-2- methoxypyridine)- ...)
Copy SMILES
Affinity Data
IC50: 3.39nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765920
((1R,4R)-4-((6-(3- ((2,5-dichloro-3- (hydroxymethyl...)
Copy SMILES
Affinity Data
IC50: 3.94nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765944
(5-chloro-N-(3-(2- (((1R,4R)-4- (dimethylamino)cy- ...)
Copy SMILES
Affinity Data
IC50: 3.95nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765926
(5-chloro-N-(2,4- difluoro-3-(2- (((1R,3R)-3-(((2- ...)
Copy SMILES
Affinity Data
IC50: 3.96nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765928
((2R,4S)-4-((6-(3- ((5-chloro-2- methoxypyridine)- ...)
Copy SMILES
Affinity Data
IC50: 4.18nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765941
(N-(3-(2- (((1R,4R)-4- aminocyclohexyl) amino)-8- e...)
Copy SMILES
Affinity Data
IC50: 5.13nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765919
((2R,4S)-4-((6-(3- ((2,5-dichloro-3- (hydroxymethyl...)
Copy SMILES
Affinity Data
IC50: 5.43nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765934
(5-chloro-N-(3-(2- ((1,1- dioxidotetrahydro- thioph...)
Copy SMILES
Affinity Data
IC50: 6.66nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765937
(N-(4-(2-amino-8- ethylquinazolin- 6-yl)-3,5- diflu...)
Copy SMILES
Affinity Data
IC50: 7.32nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765925
(2,5-dichloro-N- (3-(2-((1,1- dioxidotetrahydro- th...)
Copy SMILES
Affinity Data
IC50: 7.62nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765938
(N-(4-(2-amino-8- ethylquinazolin- 6-yl)-3,5- dichl...)
Copy SMILES
Affinity Data
IC50: 8.33nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765936
(N-(4-(2-amino-8- ethylquinazolin- 6-yl)-3,5- dichl...)
Copy SMILES
Affinity Data
IC50: 8.82nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765930
((2R,4S)-4-((6- (2,6-dichloro-3- ((5-chloro-2- meth...)
Copy SMILES
Affinity Data
IC50: 9.17nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765932
((1R,4R)-4-((6-(3- ((5-chloro-2- methoxypyridine)- ...)
Copy SMILES
Affinity Data
IC50: 10.2nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765917
((R)-3-((6-(3- ((2,5-dichloro-3- (hydroxymethyl)phe...)
Copy SMILES
Affinity Data
IC50: 10.4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765921
((R)-3-((6-(3-((5- chloro-2- methoxypyridine)- 3-su...)
Copy SMILES
Affinity Data
IC50: 11.4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765929
((1R,3R)-3-((6- (2,6-dichloro-3- ((5-chloro-2- meth...)
Copy SMILES
Affinity Data
IC50: 11.7nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765923
(5-chloro-N-(2,4- dichloro-3-(2- (((1R,3R)-3-(((2- ...)
Copy SMILES
Affinity Data
IC50: 12.6nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765953
(N-(4-(2- aminoquinazolin- 6-yl)-3,5- dichloropyrid...)
Copy SMILES
Affinity Data
IC50: 19.4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765935
(5-chloro-N-(2,4- dichloro-3-(2- ((1,1- dioxidotetr...)
Copy SMILES
Affinity Data
IC50: 25.3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765947
(2-chloro-N-(3-(2- (((1R,4R)-4- (dimethylamino)cy- ...)
Copy SMILES
Affinity Data
IC50: 26.8nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765933
((1R,4R)-4-((6- (2,6-dichloro-3- ((5-chloro-2- meth...)
Copy SMILES
Affinity Data
IC50: 31.9nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765943
((1R,3R)-3-((6-(3- ((5-chloro-2- methoxypyridine)- ...)
Copy SMILES
Affinity Data
IC50: 34.3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765950
(N-(3-(2- (((1R,4R)-4- aminocyclohexyl) amino)-8- e...)
Copy SMILES
Affinity Data
IC50: 39.8nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765931
((R)-3-((6-(2,6- dichloro-3-((5- chloro-2- methoxyp...)
Copy SMILES
Affinity Data
IC50: 41.6nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765948
(2-chloro-N-(3-(8- ethyl-2-(((1R,4R)- 4- (methylami...)
Copy SMILES
Affinity Data
IC50: 43.7nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765949
(2-chloro-N-(2,4- difluoro-3-(2- (((1R,4R)-4- (meth...)
Copy SMILES
Affinity Data
IC50: 63.2nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765951
(2-chloro-N-(3-(2- (((1R,4R)-4- (dimethylamino)cy- ...)
Copy SMILES
Affinity Data
IC50: 81.2nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765939
(5-chloro-N-(3-(8- ethyl-2-(((1R,4R)- 4- (methylami...)
Copy SMILES
Affinity Data
IC50: 88.3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765952
(N-(3-(2- (((1R,4R)-4- aminocyclohexyl) amino)quina...)
Copy SMILES
Affinity Data
IC50: 123nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
eIF-2-alpha kinase GCN2
(Human)
TBA
Ligand
BDBM765954
(N-(4-(2- aminoquinazolin- 6-yl)-3,5- difluoropyrid...)
Copy SMILES
Affinity Data
IC50: 367nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
TBA
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL