Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 13205
LigandPNGBDBM766905(N-(2-(3- (Dimethylamino)a- zetidin-1-yl)-5-(3'- me...)
Affinity DataIC50: 0.120nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 0.630nMAssay Description:On day one, a 96-well plate (ThermoFisher, Cat #: 442404) was coated with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50635714(CHEMBL5558159 | US20250268873, Compound 569)
Affinity DataIC50: 0.630nMAssay Description:On day one, a 96-well plate (ThermoFisher, Cat #: 442404) was coated with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766902(N-(5-(7'-Fluoro-3'-methyl-2'-oxo-2',3'-dihydrospir...)
Affinity DataIC50: 0.790nMAssay Description:On day one, a 96-well plate (ThermoFisher, Cat #: 442404) was coated with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766905(N-(2-(3- (Dimethylamino)a- zetidin-1-yl)-5-(3'- me...)
Affinity DataIC50: 1.03nMAssay Description:On day one, a 96-well plate (ThermoFisher, Cat #: 442404) was coated with GST-p53 (1-101) peptide (purified by Pharmaron, BCS department) by diluting...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766905(N-(2-(3- (Dimethylamino)a- zetidin-1-yl)-5-(3'- me...)
Affinity DataIC50: 3nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50635714(CHEMBL5558159 | US20250268873, Compound 569)
Affinity DataIC50: 16nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766902(N-(5-(7'-Fluoro-3'-methyl-2'-oxo-2',3'-dihydrospir...)
Affinity DataIC50: 18nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766905(N-(2-(3- (Dimethylamino)a- zetidin-1-yl)-5-(3'- me...)
Affinity DataIC50: 19.9nMAssay Description:mTOR Kinase reactions were performed in a 10 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008260 plates were used. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 21nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766902(N-(5-(7'-Fluoro-3'-methyl-2'-oxo-2',3'-dihydrospir...)
Affinity DataIC50: 54nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 55nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50635714(CHEMBL5558159 | US20250268873, Compound 569)
Affinity DataIC50: 73nMAssay Description:PI3Kα and PI3Kδ Kinase reactions were performed in a 5 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008280 plates were used...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766904(N-(5-(7'-Fluoro-3'- | US20250268873, Compound 570)
Affinity DataIC50: 100nMAssay Description:mTOR Kinase reactions were performed in a 10 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008260 plates were used. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50635714(CHEMBL5558159 | US20250268873, Compound 569)
Affinity DataIC50: 100nMAssay Description:mTOR Kinase reactions were performed in a 10 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008260 plates were used. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM766902(N-(5-(7'-Fluoro-3'-methyl-2'-oxo-2',3'-dihydrospir...)
Affinity DataIC50: 100nMAssay Description:mTOR Kinase reactions were performed in a 10 μL volume in low-volume 384-well plates. Typically, PerkinElmer model 6008260 plates were used. The comp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent