Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 13215
TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767425([6-(6-Methylpyridin-2-yl)-5- {thieno[3,2-c]pyridin...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767453(6-[6-(6-Methoxypyridin-2-yl)- 1H,2H,3H-imidazo[1,2...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767446(6-[1-Ethyl-6-(6-methylpyridin-2-yl)- 1H,2H,3H-imid...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767445(6-(6-(6-Methylpyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767441(6-(1-Ethyl-6-(6-methylpyridin-2-yl)- 2,3-dihydro-1...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767438(N-methyl-6-(6-methylpyridin-2-yl)- 5-{thieno[3,2-b...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767437(5-(6-(6-methylpyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767432(6-(6-(6-Chloropyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767427(2-(5-([1,2,4]Triazolo[1,5-a]pyridin- 6-yl)-2,3-dih...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767434(2-(6-(5-Chloro-2-fluorophenyl)-2,3- dihydro-1H-imi...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767426(6-(6-(5-Chloro-2-fluorophenyl)-2,3- dihydro-1H-imi...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767433(2-(6-(6-Chloropyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767429(2-(6-(4-Methylthiazol-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767436(5-(6-(6-Methylpyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767428(6-(6-Methylpyridin-2-yl)-5- {thieno[3,2-c]pyridin-...)
Affinity DataIC50: 1nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767448(2-(1-Ethyl-5-{thieno[3,2-c]pyridin- 2-yl}-1H,2H,3H...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767447(4-(6-(6-Methylpyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767442(Ethyl 6-(6-methylpyridin-2-yl)-5- {[1,2,4]triazolo...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767444(5-(6-(6-Methylpyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767443(N,N-Dimethyl-6-(6-methylpyridin- 2-yl)-5-{thieno[3...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767431(2-(6-(1-Methyl-1H-pyrazol-3-yl)- 2,3-dihydro-1H-im...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767440(2-[6-(6-Methylpyridin-2-yl)-5- {thieno[3,2-c]pyrid...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767439(Ethyl 2-[6-(6-methylpyridin-2-yl)-5- {thieno[3,2-c...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767450(6-(6-(6-Methylpyridin-2-yl)-2,3-dihydro-1H-imidazo...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767449(2-Fluoro-5-(6-(6-methylpyridin- 2-yl)-2,3-dihydro-...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767451(4-[6-(6-Methylpyridin-2-yl)- 1H,2H,3H-imidazo[1,2-...)
Affinity DataIC50: 3nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767430(6-(6-(1-Methyl-1H-pyrazol-3-yl)- 2,3-dihydro-1H-im...)
Affinity DataIC50: 7.5nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767452(4-[6-(6-Methylpyridin-2-yl)- 1H,2H,3H-imidazo[1,2-...)
Affinity DataIC50: 7.5nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent

TargetTGF-beta receptor type-1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM767435(1-(6-(6-Methylpyridin-2-yl)-2,3- dihydro-1H-imidaz...)
Affinity DataIC50: 7.5nMAssay Description:Briefly, the kinase reaction was performed by incubating 2.6 nM of the purified, commercially available human ALK5 (recombinant TGF β1 N-term GST-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/9/2025
Entry Details
US Patent