Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 13299
TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775051(US20250304585, Compound 3c)
Affinity DataIC50: 8.60nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 12nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775052(US20250304585, Compound 3d)
Affinity DataIC50: 24nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775054(US20250304585, Compound 3g)
Affinity DataIC50: 24nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775049(US20250304585, Compound 3a)
Affinity DataIC50: 29nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775050(US20250304585, Compound 3b)
Affinity DataIC50: 46nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775064(US20250304585, Compound A7)
Affinity DataIC50: 63nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775068(US20250304585, Compound A11)
Affinity DataIC50: 72nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775066(US20250304585, Compound A9)
Affinity DataIC50: 88nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775053(US20250304585, Compound 3e)
Affinity DataIC50: 95nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775067(US20250304585, Compound A10)
Affinity DataIC50: 96nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775065(US20250304585, Compound A8)
Affinity DataIC50: 120nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775051(US20250304585, Compound 3c)
Affinity DataIC50: 241nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775049(US20250304585, Compound 3a)
Affinity DataIC50: 261nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775053(US20250304585, Compound 3e)
Affinity DataIC50: 275nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM627846(CVD-0017756 | US20250304585, Compound C)
Affinity DataIC50: 307nMAssay Description:Not specidied.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775063(US20250304585, Compound A6)
Affinity DataIC50: 316nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM496755(DAV-CRI-14a23e73-1 | CVD-0000864 | US20250304585, ...)
Affinity DataIC50: 466nMAssay Description:Not specidied.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775052(US20250304585, Compound 3d)
Affinity DataIC50: 533nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM495624(JOH-UNI-0e1753c1-5 | CVD-0016253 | US20250304585, ...)
Affinity DataIC50: 700nMAssay Description:Not specidied.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775051(US20250304585, Compound 3c)
Affinity DataIC50: 740nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775049(US20250304585, Compound 3a)
Affinity DataIC50: 795nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775060(US20250304585, Compound A3)
Affinity DataIC50: 1.03E+3nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775062(US20250304585, Compound A5)
Affinity DataIC50: 1.10E+3nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775052(US20250304585, Compound 3d)
Affinity DataIC50: 1.28E+3nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775058(US20250304585, Compound A1)
Affinity DataIC50: 1.67E+3nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.67E+3nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775070(US20250304585, Compound B2)
Affinity DataIC50: 1.73E+3nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775069(US20250304585, Compound B1)
Affinity DataIC50: 1.77E+3nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775053(US20250304585, Compound 3e)
Affinity DataIC50: 1.96E+3nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 2.00E+3nMAssay Description:Kinase reactions are assembled in 384-well plates (Greiner) in a total volume of 20 μL. Test compounds (3a-3g) were diluted in DMSO to a final concen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775059(US20250304585, Compound A2)
Affinity DataIC50: 6.69E+3nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775073(US20250304585, Compound C3)
Affinity DataIC50: 1.63E+4nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775072(US20250304585, Compound C2)
Affinity DataIC50: 1.76E+4nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775071(US20250304585, Compound C1)
Affinity DataIC50: 8.04E+4nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yeda Research and Development Co.

US Patent
LigandPNGBDBM775061(US20250304585, Compound A4)
Affinity DataIC50: 9.95E+4nMAssay Description:Not specidied.More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent