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Found
68
Enz. Inhib. hit(s) with all data for entry = 5564
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM370148
(US20260021085, Compound 5)
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Affinity Data
IC50: 84nM
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Ligand Info
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PC sid
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In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372275
(Synthesis of (1S,2R)-2-(((R)-(3-fluoro-4-isopropyl...)
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Affinity Data
IC50: 166nM
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM369917
(US20260021085, Compound 4)
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Affinity Data
IC50: 178nM
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Ligand Info
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In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372281
(US20260021085, Compound 28)
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Affinity Data
IC50: 224nM
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Ligand Info
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PC sid
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In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372271
(US20260021085, Compound 19)
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Affinity Data
IC50: 228nM
More data for this Ligand-Target Pair
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372291
(US20260021085, Compound 37)
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IC50: 236nM
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372260
(US20260021085, Compound 8)
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Affinity Data
IC50: 239nM
More data for this Ligand-Target Pair
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM370178
(US20260021085, Compound 6)
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IC50: 272nM
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372299
(US20260021085, Compound 45)
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IC50: 364nM
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372270
(US20260021085, Compound 18)
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Affinity Data
IC50: 384nM
More data for this Ligand-Target Pair
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Ligand Info
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In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372294
(US20260021085, Compound 40)
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IC50: 390nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM369907
(US20260021085, Compound 2)
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IC50: 426nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372288
(US20260021085, Compound 34)
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IC50: 426nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372267
(US20260021085, Compound 15)
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IC50: 497nM
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Target Info
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM369908
(US20260021085, Compound 3)
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IC50: 630nM
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Target Info
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372295
(US20260021085, Compound 41)
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IC50: 637nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372279
(US20260021085, Compound 26)
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IC50: 795nM
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Target Info
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372268
(US20260021085, Compound 16)
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IC50: 836nM
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Target Info
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372290
(US20260021085, Compound 36)
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IC50: 837nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372261
(US20260021085, Compound 9)
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Affinity Data
IC50: 879nM
More data for this Ligand-Target Pair
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM370378
(Synthesis of (1S,2R)-2-(((R)-(3-fluoro-4-isopropyl...)
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Affinity Data
IC50: 884nM
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372296
(US20260021085, Compound 42)
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Affinity Data
IC50: 961nM
More data for this Ligand-Target Pair
Target Info
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372266
(US20260021085, Compound 14)
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Affinity Data
IC50: 1.01E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372285
(US20260021085, Compound 31)
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IC50: 1.09E+3nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372292
(US20260021085, Compound 38)
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Affinity Data
IC50: 1.13E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372278
(US20260021085, Compound 25)
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Affinity Data
IC50: 1.15E+3nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372274
(US20260021085, Compound 22)
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IC50: 1.27E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM369880
(US20260021085, Compound 1)
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IC50: 1.44E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372280
(US20260021085, Compound 27)
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IC50: 1.48E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372282
(US20260021085, Compound 29)
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IC50: 1.52E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372269
(US20260021085, Compound 17)
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IC50: 1.58E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372284
(US20260021085, Compound 30)
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IC50: 1.61E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372264
(US20260021085, Compound 12)
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IC50: 1.73E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372263
(US20260021085, Compound 11)
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IC50: 1.95E+3nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372273
(US20260021085, Compound 21)
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IC50: 1.96E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372265
(US20260021085, Compound 13)
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IC50: 2.36E+3nM
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In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372272
(US20260021085, Compound 20)
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IC50: 2.38E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372286
(US20260021085, Compound 32)
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IC50: 2.39E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372289
(US20260021085, Compound 35)
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IC50: 2.40E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372276
(US20260021085, Compound 24)
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IC50: 2.82E+3nM
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Ligand Info
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Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372262
(US20260021085, Compound 10)
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IC50: 2.93E+3nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372287
(US20260021085, Compound 33)
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IC50: 3.13E+3nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372293
(US20260021085, Compound 39)
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IC50: 3.41E+3nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, liver/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372281
(US20260021085, Compound 28)
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IC50: 7.80E+3nM
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Ligand Info
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PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, liver/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372275
(Synthesis of (1S,2R)-2-(((R)-(3-fluoro-4-isopropyl...)
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Affinity Data
IC50: 8.48E+3nM
More data for this Ligand-Target Pair
Target Info
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GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, liver/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372294
(US20260021085, Compound 40)
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Affinity Data
IC50: 1.08E+4nM
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UniProtKB/SwissProt
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Ligand Info
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PC sid
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In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, liver/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372298
(US20260021085, Compound 44)
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IC50: 1.17E+4nM
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Target Info
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372298
(US20260021085, Compound 44)
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Affinity Data
IC50: 1.29E+4nM
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Target Info
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, liver/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372279
(US20260021085, Compound 26)
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Affinity Data
IC50: 1.55E+4nM
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Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
Copy reaction URL
Target
Glycogen [starch] synthase, muscle/Glycogenin-1 (GN1)
(Human)
Maze Therapeutics
US Patent
Ligand
BDBM372297
(US20260021085, Compound 43)
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Affinity Data
IC50: 1.98E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent
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