Report error Found 295 Enz. Inhib. hit(s) with all data for entry = 7628
Affinity DataIC50: 16.3nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 18.7nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 19.1nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 21.3nMAssay Description:CHO cells were transfected with an expression vector encoding rat 5-HT7 gene and CRE-Luc reporter system. Colonies were isolated and screened with 10...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 22.8nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 23.2nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 24.5nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 25.1nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 26.5nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 27.8nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 28.8nMAssay Description:Muscarinic acetylcholine receptor M1 was cloned into an expression vector and transfected in CHO cells along with CRE-Luc reporter system. Isolated c...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 28.9nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 36nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 41nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:CHO cells stably expressing human TRPV1 (hTRPV1) were used. Functional assessment of heat-induced activation of hTRPV1 was carried out in a cell-base...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Inhibition of O-GlcNAcase, which removes O-GlcNAc from cellular proteins, results in an increase in the level of O-GlcNAcylated protein in cells. An ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Inhibition of O-GlcNAcase, which removes O-GlcNAc from cellular proteins, results in an increase in the level of O-GlcNAcylated protein in cells. An ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Inhibition of O-GlcNAcase, which removes O-GlcNAc from cellular proteins, results in an increase in the level of O-GlcNAcylated protein in cells. An ...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:To measure cell-based anti-HCV activity of selected compounds of the present invention, replicon cells were seeded at 5000 cells/well in 96-well coll...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:To measure cell-based anti-HCV activity of selected compounds of the present invention, replicon cells were seeded at 5000 cells/well in 96-well coll...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 50nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
