Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 13169
TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793405BDBM793405(12-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-3,1...)
Affinity DataIC50: 1.60nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793405BDBM793405(12-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-3,1...)
Affinity DataIC50: 1.95nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793404BDBM793404(US20260049089, Example 5)
Affinity DataIC50: 2.06nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793403BDBM793403(US20260049089, Example 4)
Affinity DataIC50: 2.20nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793402BDBM793402(US20260049089, Example 3)
Affinity DataIC50: 2.31nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793404BDBM793404(US20260049089, Example 5)
Affinity DataIC50: 2.63nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793401BDBM793401(US20260049089, Example 2)
Affinity DataIC50: 2.87nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793401BDBM793401(US20260049089, Example 2)
Affinity DataIC50: 3.23nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793402BDBM793402(US20260049089, Example 3)
Affinity DataIC50: 3.24nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793403BDBM793403(US20260049089, Example 4)
Affinity DataIC50: 3.5nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793405BDBM793405(12-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-3,1...)
Affinity DataIC50: 58.5nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793403BDBM793403(US20260049089, Example 4)
Affinity DataIC50: 94.4nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793404BDBM793404(US20260049089, Example 5)
Affinity DataIC50: 232nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793406BDBM793406(US20260049089, Example 11)
Affinity DataIC50: 500nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793406BDBM793406(US20260049089, Example 11)
Affinity DataIC50: 726nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793406BDBM793406(US20260049089, Example 11)
Affinity DataIC50: 909nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793401BDBM793401(US20260049089, Example 2)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent

TargetGTPase KRas (G12D)(Human)
Shanghai Apeiron Therapeutics Company

US Patent
LigandChemical structure of BindingDB Monomer ID 793402BDBM793402(US20260049089, Example 3)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/1/2026
Entry Details
US Patent