Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 13441
TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757247BDBM757247(US20250223284, Example Table 2.12 | US20260055093,...)
Affinity DataIC50: 2.36nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757247BDBM757247(US20250223284, Example Table 2.12 | US20260055093,...)
Affinity DataIC50: 3.04nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757246BDBM757246(US20250223284, Example Table 2.11 | US20260055093,...)
Affinity DataIC50: 4.20nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757246BDBM757246(US20250223284, Example Table 2.11 | US20260055093,...)
Affinity DataIC50: 4.20nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757292BDBM757292(US20250223284, Example Table 3.39 | US20260055093,...)
Affinity DataIC50: 4.91nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757292BDBM757292(US20250223284, Example Table 3.39 | US20260055093,...)
Affinity DataIC50: 6.05nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793797BDBM793797(US20260055093, Compound Table3.48)
Affinity DataIC50: 6.82nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793749BDBM793749(US20260055093, Example Table2.21)
Affinity DataIC50: 7.04nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757251BDBM757251(US20250223284, Example Table 2.16 | US20260055093,...)
Affinity DataIC50: 13.1nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757264BDBM757264(US20250223284, Example Table 3.11 | US20260055093,...)
Affinity DataIC50: 13.6nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757263BDBM757263(US20250223284, Example Table 3.10 | US20260055093,...)
Affinity DataIC50: 14.1nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757251BDBM757251(US20250223284, Example Table 2.16 | US20260055093,...)
Affinity DataIC50: 15.8nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757295BDBM757295(US20250223284, Example Table 3.42 | US20260055093,...)
Affinity DataIC50: 17.4nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757249BDBM757249(US20250223284, Example Table 2.14 | US20260055093,...)
Affinity DataIC50: 17.8nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757283BDBM757283(US20250223284, Example Table 3.30 | US20260055093,...)
Affinity DataIC50: 22.3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757288BDBM757288(US20250223284, Example Table 3.35 | US20260055093,...)
Affinity DataIC50: 23.2nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757283BDBM757283(US20250223284, Example Table 3.30 | US20260055093,...)
Affinity DataIC50: 25.1nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757243BDBM757243(US20250223284, Example Table 2.8 | US20260055093, ...)
Affinity DataIC50: 25.1nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757293BDBM757293(US20250223284, Example Table 3.40 | US20260055093,...)
Affinity DataIC50: 27nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757249BDBM757249(US20250223284, Example Table 2.14 | US20260055093,...)
Affinity DataIC50: 30.9nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757283BDBM757283(US20250223284, Example Table 3.30 | US20260055093,...)
Affinity DataIC50: 33.9nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757243BDBM757243(US20250223284, Example Table 2.8 | US20260055093, ...)
Affinity DataIC50: 36.9nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793751BDBM793751(US20260055093, Example 2-A | US20260055093, Compou...)
Affinity DataIC50: 39.6nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757283BDBM757283(US20250223284, Example Table 3.30 | US20260055093,...)
Affinity DataIC50: 41.4nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757258BDBM757258(US20250223284, Example Table 3.5 | US20260055093, ...)
Affinity DataIC50: 49.8nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793730BDBM793730(US20260055093, Example 2-A | US20260055093, Exampl...)
Affinity DataIC50: 51.7nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757258BDBM757258(US20250223284, Example Table 3.5 | US20260055093, ...)
Affinity DataIC50: 54nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757260BDBM757260(US20250223284, Example Table 3.7 | US20260055093, ...)
Affinity DataIC50: 61.3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793729BDBM793729(US20260055093, Example 1-A | US20260055093, Exampl...)
Affinity DataIC50: 63.4nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757286BDBM757286(US20250223284, Example Table 3.33 | US20260055093,...)
Affinity DataIC50: 67.4nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793750BDBM793750(US20260055093, Example 1-A | US20260055093, Compou...)
Affinity DataIC50: 72.6nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757295BDBM757295(US20250223284, Example Table 3.42 | US20260055093,...)
Affinity DataIC50: 74.7nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757260BDBM757260(US20250223284, Example Table 3.7 | US20260055093, ...)
Affinity DataIC50: 85.6nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757281BDBM757281(US20250223284, Example Table 3.28 | US20260055093,...)
Affinity DataIC50: 95.9nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793731BDBM793731(US20260055093, Example 3-A | US20260055093, Exampl...)
Affinity DataIC50: 130nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757297BDBM757297(US20250223284, Example Table 3.44 | US20260055093,...)
Affinity DataIC50: 140nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793752BDBM793752(US20260055093, Example 3-A | US20260055093, Compou...)
Affinity DataIC50: 145nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757297BDBM757297(US20250223284, Example Table 3.44 | US20260055093,...)
Affinity DataIC50: 148nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757285BDBM757285(US20250223284, Example Table 3.32 | US20260055093,...)
Affinity DataIC50: 198nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793753BDBM793753(US20260055093, Compound Table3.4)
Affinity DataIC50: 206nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757282BDBM757282(US20250223284, Example Table 3.29 | US20260055093,...)
Affinity DataIC50: 230nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757277BDBM757277(US20250223284, Example Table 3.24 | US20260055093,...)
Affinity DataIC50: 234nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757287BDBM757287(US20250223284, Example Table 3.34 | US20260055093,...)
Affinity DataIC50: 243nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793732BDBM793732(US20260055093, Example 3-B | US20260055093, Exampl...)
Affinity DataIC50: 251nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757262BDBM757262(US20250223284, Example Table 3.9 | US20260055093, ...)
Affinity DataIC50: 314nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757262BDBM757262(US20250223284, Example Table 3.9 | US20260055093, ...)
Affinity DataIC50: 351nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757290BDBM757290(US20250223284, Example Table 3.37 | US20260055093,...)
Affinity DataIC50: 457nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757253BDBM757253(US20250223284, Example Table 2.18 | US20260055093,...)
Affinity DataIC50: 603nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757253BDBM757253(US20250223284, Example Table 2.18 | US20260055093,...)
Affinity DataIC50: 629nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 757279BDBM757279(US20250223284, Example Table 3.26 | US20260055093,...)
Affinity DataIC50: 729nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

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