Compile Data Set for Download or QSAR
Report error Found 183 Enz. Inhib. hit(s) with all data for entry = 13445
TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793879BDBM793879(US20260055108, Compound 93)
Affinity DataIC50: 0.600nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793943BDBM793943(US20260055108, Compound 110)
Affinity DataIC50: 0.700nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793944BDBM793944(US20260055108, Compound 154)
Affinity DataIC50: 0.800nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793883BDBM793883(US20260055108, Compound 94)
Affinity DataIC50: 0.800nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793961BDBM793961(US20260055108, Compound 26)
Affinity DataIC50: 0.900nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793895BDBM793895(US20260055108, Compound 97)
Affinity DataIC50: 0.900nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793911BDBM793911(US20260055108, Compound 101)
Affinity DataIC50: 0.900nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793931BDBM793931(US20260055108, Compound 106)
Affinity DataIC50: 0.900nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794018BDBM794018(US20260055108, Compound 84)
Affinity DataIC50: 0.900nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793890BDBM793890(US20260055108, Compound 52)
Affinity DataIC50: 0.900nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793985BDBM793985(US20260055108, Compound 32)
Affinity DataIC50: 1nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794026BDBM794026(US20260055108, Compound 86)
Affinity DataIC50: 1.10nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793866BDBM793866(US20260055108, Compound 46)
Affinity DataIC50: 1.10nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794034BDBM794034(US20260055108, Compound 88)
Affinity DataIC50: 1.10nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793946BDBM793946(US20260055108, Compound 66)
Affinity DataIC50: 1.20nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793864BDBM793864(US20260055108, Compound 134)
Affinity DataIC50: 1.30nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793987BDBM793987(US20260055108, Compound 121)
Affinity DataIC50: 1.5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794028BDBM794028(US20260055108, Compound 175)
Affinity DataIC50: 1.5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793932BDBM793932(US20260055108, Compound 151)
Affinity DataIC50: 1.5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793977BDBM793977(US20260055108, Compound 30)
Affinity DataIC50: 1.70nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794009BDBM794009(US20260055108, Compound 38)
Affinity DataIC50: 1.70nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793907BDBM793907(US20260055108, Compound 100)
Affinity DataIC50: 1.90nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793955BDBM793955(US20260055108, Compound 113)
Affinity DataIC50: 1.90nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794035BDBM794035(US20260055108, Compound 133)
Affinity DataIC50: 2nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793867BDBM793867(US20260055108, Compound 90)
Affinity DataIC50: 2.10nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793969BDBM793969(US20260055108, Compound 28)
Affinity DataIC50: 2.20nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793959BDBM793959(US20260055108, Compound 114)
Affinity DataIC50: 2.30nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793979BDBM793979(US20260055108, Compound 119)
Affinity DataIC50: 2.30nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793869BDBM793869(US20260055108, Compound 3)
Affinity DataIC50: 2.40nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793973BDBM793973(US20260055108, Compound 29)
Affinity DataIC50: 2.5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794010BDBM794010(US20260055108, Compound 82)
Affinity DataIC50: 2.60nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793992BDBM793992(US20260055108, Compound 166)
Affinity DataIC50: 2.60nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793870BDBM793870(US20260055108, Compound 47)
Affinity DataIC50: 2.60nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794023BDBM794023(US20260055108, Compound 130)
Affinity DataIC50: 2.70nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794031BDBM794031(US20260055108, Compound 132)
Affinity DataIC50: 2.70nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793863BDBM793863(US20260055108, Compound 89)
Affinity DataIC50: 2.80nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793989BDBM793989(US20260055108, Compound 33)
Affinity DataIC50: 2.90nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793924BDBM793924(US20260055108, Compound 149)
Affinity DataIC50: 2.90nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793910BDBM793910(US20260055108, Compound 57)
Affinity DataIC50: 3nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794021BDBM794021(US20260055108, Compound 41)
Affinity DataIC50: 3.10nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793871BDBM793871(US20260055108, Compound 91)
Affinity DataIC50: 3.10nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793873BDBM793873(US20260055108, Compound 4)
Affinity DataIC50: 3.20nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793887BDBM793887(US20260055108, Compound 95)
Affinity DataIC50: 3.20nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794024BDBM794024(US20260055108, Compound 107)
Affinity DataIC50: 3.30nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793902BDBM793902(US20260055108, Compound 55)
Affinity DataIC50: 3.5nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794038BDBM794038(US20260055108, Compound 180)
Affinity DataIC50: 3.90nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 793862BDBM793862(US20260055108, Compound 45)
Affinity DataIC50: 3.90nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794043BDBM794043(US20260055108, Compound 183)
Affinity DataIC50: 4nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794022BDBM794022(US20260055108, Compound 85)
Affinity DataIC50: 4.20nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

TargetMenin [2-610](Human)
Hutchmed

US Patent
LigandChemical structure of BindingDB Monomer ID 794033BDBM794033(US20260055108, Compound 44)
Affinity DataIC50: 4.30nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details
US Patent

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