Compile Data Set for Download or QSAR
Report error Found 348 Enz. Inhib. hit(s) with all data for entry = 13473
TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796225BDBM796225(5-((3-(3-((3-chloro-4-cyclobutoxy-benzyl)amino)pro...)
Affinity DataIC50: 0.180nMAssay Description:Representative compounds of the present invention were additionally tested in an in vitro assay measuring inhibition of CSF-1 induced monocyte MCP-1 ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796124BDBM796124(5-{[3-({4-[({2-chloro-[1,1'-biphenyl]-4-yl}methyl)...)
Affinity DataIC50: 0.180nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796185BDBM796185(5-((2-(4-(2-(((2-Chloro-[1,1'-biphenyl]-4-yl)methy...)
Affinity DataIC50: 0.190nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796275BDBM796275(5-((3-((3-((3-Chloro-4-(trifluoromethoxy)benzyl)am...)
Affinity DataIC50: 0.200nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796167BDBM796167(5-((3-(3-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)a...)
Affinity DataIC50: 0.200nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796126BDBM796126(5-(3-(3-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)am...)
Affinity DataIC50: 0.210nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796127BDBM796127(5-((2-(4-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)a...)
Affinity DataIC50: 0.210nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796122BDBM796122(5-[4-({4-[({2-chloro-[1,1'-biphenyl]-4-yl}methyl)a...)
Affinity DataIC50: 0.210nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796273BDBM796273(5-((3-(3-((3-Chloro-4-(trifluoromethoxy)benzyl)ami...)
Affinity DataIC50: 0.220nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796227BDBM796227(5-((3-(3-((3-Fluoro-4-(trifluorometh-oxy)benzyl)am...)
Affinity DataIC50: 0.240nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796159BDBM796159(5-((3-(3-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)a...)
Affinity DataIC50: 0.240nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796224BDBM796224(5-((3-(3-((3-chloro-4-(cyclopentyl-oxy)benzyl)amin...)
Affinity DataIC50: 0.25nMAssay Description:Representative compounds of the present invention were additionally tested in an in vitro assay measuring inhibition of CSF-1 induced monocyte MCP-1 ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796190BDBM796190(5-((2-((4-(((5-(Trifluoromethyl)-1H-indol-2-yl)met...)
Affinity DataIC50: 0.260nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796292BDBM796292(5-(4-(4-((3,5-Difluoro-4-(trifluoromethoxy)benzyl)...)
Affinity DataIC50: 0.290nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796254BDBM796254(5-((3-(3-((3,5-Difluoro-4-(trifluoromethoxy)benzyl...)
Affinity DataIC50: 0.300nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796195BDBM796195(N1-(2-((8-(2H-tetrazol-5-yl)benzo[c][2,6]naphthyri...)
Affinity DataIC50: 0.300nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796221BDBM796221(5-((3-(3-((3-Chloro-4-(trifluoromethoxy)benzyl)ami...)
Affinity DataIC50: 0.300nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796276BDBM796276(5-((4-(2-((3-Chloro-4-(trifluoromethoxy)benzyl)ami...)
Affinity DataIC50: 0.310nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796229BDBM796229(5-((3-(3-((3,5-Dichlorobenzyl)amino)propanamido)pr...)
Affinity DataIC50: 0.310nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796188BDBM796188(5-((2-((4-((3-Chloro-4-(trifluoromethoxy)benzyl)am...)
Affinity DataIC50: 0.320nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796219BDBM796219(5-((4-(4-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)a...)
Affinity DataIC50: 0.320nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796284BDBM796284(N-(3-((8-(2H-tetrazol-5-yl)benzo[c][2,6]naphthyrid...)
Affinity DataIC50: 0.320nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796248BDBM796248(5-((3-(3-((3-cyano-4-cyclobutoxy-benzyl)amino)prop...)
Affinity DataIC50: 0.330nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796223BDBM796223(5-((3-(3-((3-Chloro-4-cyclopropylbenzyl)amino)prop...)
Affinity DataIC50: 0.330nMAssay Description:Representative compounds of the present invention were additionally tested in an in vitro assay measuring inhibition of CSF-1 induced monocyte MCP-1 ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796283BDBM796283((S)-5-(3-(3-((3-Chloro-4-(trifluoromethoxy)benzyl)...)
Affinity DataIC50: 0.360nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796222BDBM796222(5-((3-(3-((3-Chloro-4-cyclopropoxybenzyl)amino)pro...)
Affinity DataIC50: 0.360nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796277BDBM796277(5-((4-((2-((3-Chloro-4-(trifluoromethoxy)benzyl)am...)
Affinity DataIC50: 0.360nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796249BDBM796249(5-((3-(3-(((2-cyano-[1,1'-biphenyl]-4-yl)methyl)am...)
Affinity DataIC50: 0.370nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796172BDBM796172(5-((2-(4-(2-(((2-Chloro-[1,1'-biphenyl]-4-yl)methy...)
Affinity DataIC50: 0.370nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796271BDBM796271(5-((3-(3-((3-Chloro-4-cyclobutoxybenzyl)amino)prop...)
Affinity DataIC50: 0.370nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796294BDBM796294(5-(2-((3-((3,5-Difluoro-4-(trifluoromethoxy)benzyl...)
Affinity DataIC50: 0.370nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796123BDBM796123(5-{[2-({4-[({2-chloro-[1,1'-biphenyl]-4-yl}methyl)...)
Affinity DataIC50: 0.390nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796187BDBM796187(4-((3-(3-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)a...)
Affinity DataIC50: 0.400nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796295BDBM796295((S)-5-(2-((4-((3,5-difluoro-4-(trifluoromethoxy)be...)
Affinity DataIC50: 0.410nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796270BDBM796270(5-((3-(3-((3-(2-Hydroxyethoxy)benzyl)amino)propana...)
Affinity DataIC50: 0.410nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796285BDBM796285(N-(3-((8-(2H-tetrazol-5-yl)benzo[c][2,6]naphthyrid...)
Affinity DataIC50: 0.420nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796220BDBM796220(5-((3-(3-((3-Chlorobenzyl)amino)propanamido)propyl...)
Affinity DataIC50: 0.430nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796278BDBM796278(5-((2-(4-((3-Chloro-4-(trifluoromethoxy)benzyl)ami...)
Affinity DataIC50: 0.430nMAssay Description:Compounds 2a and 3a were investigated for their antiviral activity against the replication of SARS-CoV-2. Briefly, confluent Vero E6 cells were inocu...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796157BDBM796157(5-((2-((4-((3-Cyano-4-cyclobutoxy-benzyl)amino)but...)
Affinity DataIC50: 0.430nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796170BDBM796170(5-((3-(3-(((2-Chloro-[1,1'-biphenyl]-4-yl)methyl)a...)
Affinity DataIC50: 0.430nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796156BDBM796156(5-((2-((4-((3-Chloro-4-cyclobutoxy-benzyl)amino)bu...)
Affinity DataIC50: 0.440nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796274BDBM796274(5-((3-(3-((3-Chloro-4-(trifluoromethoxy)benzyl)ami...)
Affinity DataIC50: 0.450nMAssay Description:CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796238BDBM796238(5-((3-(3-((3-Chloro-4-cyclopentyl-benzyl)amino)pro...)
Affinity DataIC50: 0.460nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796128BDBM796128(5-((2-((4-(((2-chloro-[1,1'-biphenyl]-4-yl)methyl)...)
Affinity DataIC50: 0.460nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796286BDBM796286(N-(2-(4-(2-(((2-chloro-[1,1'-biphenyl]-4-yl)methyl...)
Affinity DataIC50: 0.470nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO OX1 or CHO OX2 cells were seeded into black-walled clear-base 384-well plates (Corning, catalog #3712) at a...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796201BDBM796201(5-((4-(2-(((2-chloro-[1,1'-biphenyl]-4-yl)methyl)a...)
Affinity DataIC50: 0.470nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796226BDBM796226(5-((3-(3-(((6-Chloro-1H-indol-2-yl)methyl)amino)pr...)
Affinity DataIC50: 0.490nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796209BDBM796209(5-((3-((3-((3-Chloro-4-(trifluoromethoxy)benzyl)am...)
Affinity DataIC50: 0.5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796231BDBM796231(5-((3-(3-((3-Chloro-5-fluorobenzyl)amino)prop-anam...)
Affinity DataIC50: 0.510nMAssay Description:Compounds of the present invention were tested for RORγ inverse agonist activity in a cell-based, transcriptional activity assay. Secreted Nanol...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

TargetCasein kinase II subunit alpha(Human)
Cambridge Enterprise

US Patent
LigandChemical structure of BindingDB Monomer ID 796216BDBM796216(5-((2-(3-(2-((3-Chloro-4-(trifluoromethoxy)benzyl)...)
Affinity DataIC50: 0.530nMAssay Description:he CisBio cAMP cell based assay kit that uses HTRF technology was utilized to assess MOR-mediated inhibition of cAMP. Assays were performed according...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

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