Compile Data Set for Download or QSAR
Report error Found 88 Enz. Inhib. hit(s) with all data for entry = 13475
LigandChemical structure of BindingDB Monomer ID 796524BDBM796524((3R,4R)-4-((7-((2S,4S)-2-Methylpiperidin-4-yl)-6-(...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796540BDBM796540(US20260070915, Example 28)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796523BDBM796523((3R,4R)-4-((7-((2S,4S)-2-Methylpiperidin-4-yl)-6-(...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796539BDBM796539(US20260070915, Example 27)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796523BDBM796523((3R,4R)-4-((7-((2S,4S)-2-Methylpiperidin-4-yl)-6-(...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796544BDBM796544((3S,4R)-4-((7-(4- ((Dimethylamino)methyl)- 3-fluor...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796526BDBM796526((3R,4R)-4-((7-((2S,4S)-1,2-dimethylpiperidin-4-yl)...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796542BDBM796542(US20260070915, Example 30)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796525BDBM796525((3R,4R)-4-((7-((2S,4S)-1,2-dimethylpiperidin-4-yl)...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796541BDBM796541(US20260070915, Example 29)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796525BDBM796525((3R,4R)-4-((7-((2S,4S)-1,2-dimethylpiperidin-4-yl)...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796528BDBM796528(US20260070915, Example 16)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796550BDBM796550((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)-3- fluorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796551BDBM796551((3S,4R)-4-((7-(4- ((Dimethylamino)methyl)- 3-fluor...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796528BDBM796528(US20260070915, Example 16)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796544BDBM796544((3S,4R)-4-((7-(4- ((Dimethylamino)methyl)- 3-fluor...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796551BDBM796551((3S,4R)-4-((7-(4- ((Dimethylamino)methyl)- 3-fluor...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796527BDBM796527(US20260070915, Example 15)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796543BDBM796543((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)- 2,5-diflu...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796552BDBM796552((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)- 2,5-diflu...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796543BDBM796543((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)- 2,5-diflu...)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796552BDBM796552((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)- 2,5-diflu...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796514BDBM796514(US20260070915, Example 2)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796530BDBM796530(US20260070915, Example 18)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796545BDBM796545((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)-3- fluorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796545BDBM796545((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)-3- fluorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796514BDBM796514(US20260070915, Example 2)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796530BDBM796530(US20260070915, Example 18)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796546BDBM796546((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)-3- fluorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796547BDBM796547((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)- 2,5-diflu...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796547BDBM796547((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)- 2,5-diflu...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796513BDBM796513(US20260070915, Example 1)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796529BDBM796529(US20260070915, Example 17)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796548BDBM796548((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)-3- fluorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796549BDBM796549((3S,4R)-4-((7-(4- ((Dimethylamino)methyl)- 3-fluor...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796513BDBM796513(US20260070915, Example 1)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796529BDBM796529(US20260070915, Example 17)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796550BDBM796550((3S,4R)-4-((7-(4- (Azetidin-1-ylmethyl)-3- fluorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796516BDBM796516(US20260070915, Example 4)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796532BDBM796532(US20260070915, Example 20)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796556BDBM796556((3S,4R)-4-((7-(4- (azetidin-1-ylmethyl)-3- chlorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796516BDBM796516(US20260070915, Example 4)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796532BDBM796532(US20260070915, Example 20)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796556BDBM796556((3S,4R)-4-((7-(4- (azetidin-1-ylmethyl)-3- chlorop...)
Affinity DataIC50: 10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796515BDBM796515(US20260070915, Example 3)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796531BDBM796531(US20260070915, Example 19)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796515BDBM796515(US20260070915, Example 3)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796531BDBM796531(US20260070915, Example 19)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796518BDBM796518(US20260070915, Example 6)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 796534BDBM796534(US20260070915, Example 22)
Affinity DataIC50: 10nMAssay Description:The cell-based assay measures inhibition or reduction of Aβ40 in conditioned medium of test compound treated cells expressing amyloid precursor ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/22/2026
Entry Details
US Patent

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