Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 13478
TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796616BDBM796616((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.200nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796609BDBM796609((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.200nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796603BDBM796603((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.200nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796589BDBM796589((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.200nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796588BDBM796588((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.400nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796585BDBM796585((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.5nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796584BDBM796584((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.600nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796582BDBM796582((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.800nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796619BDBM796619((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 0.900nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796610BDBM796610((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 1.20nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796617BDBM796617((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 1.30nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796618BDBM796618((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 1.5nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796604BDBM796604((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 1.60nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796596BDBM796596((8S,11S)-13-(cyclopropylmethyl)-10-[1-(2,4-difluor...)
Affinity DataIC50: 1.60nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796614BDBM796614((8S,11S)-13-[3-(4-acetylpiperazin-1-yl)propyl]-10-...)
Affinity DataIC50: 1.70nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796601BDBM796601((8S,11S)-13-allyl-10-[1-(2,4-difluorophenyl)pyrazo...)
Affinity DataIC50: 1.90nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796611BDBM796611((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 2nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796602BDBM796602((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 2nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796622BDBM796622((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 2.10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796607BDBM796607((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 2.20nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796598BDBM796598((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 2.20nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796583BDBM796583((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 2.70nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796597BDBM796597((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 3.10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796613BDBM796613((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 3.20nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796624BDBM796624((8S,11S)-10-[1-(4-fluoro-2-methoxy-phenyl)pyrazolo...)
Affinity DataIC50: 3.5nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796586BDBM796586((8S,11S)-10-[3-(2,4-difluorophenyl)imidazo[1,5-a]p...)
Affinity DataIC50: 3.80nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796626BDBM796626((8S,11S)-21-fluoro-10-[1-(4-fluoro-2-methoxy-pheny...)
Affinity DataIC50: 3.90nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796594BDBM796594((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 4.70nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796595BDBM796595((8S,11S)-10-[1-(4-fluoro-2-methoxy-phenyl)pyrazolo...)
Affinity DataIC50: 4.80nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796587BDBM796587((8S,11S)-10-[1-(4-fluoro-2-methoxy-phenyl)pyrazolo...)
Affinity DataIC50: 5nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796591BDBM796591((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 5.10nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796623BDBM796623((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 5.30nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796620BDBM796620((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 5.5nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796625BDBM796625((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 6.30nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796615BDBM796615((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 7nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796612BDBM796612((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 7.20nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796628BDBM796628((8S,11S)-10-[1-(4-fluoro-2-methoxy-phenyl)pyrazolo...)
Affinity DataIC50: 7.20nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796627BDBM796627((8S,11S)-10-[1-(4-fluoro-2-methoxy-phenyl)pyrazolo...)
Affinity DataIC50: 7.60nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796605BDBM796605((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 8.20nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796621BDBM796621((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 8.60nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796599BDBM796599((8S,11S)-13-(cyclopropylmethyl)-10-[1-(2,4-difluor...)
Affinity DataIC50: 12.5nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796600BDBM796600((8S,11S)-13-(cyclopropylmethyl)-10-[1-(2,4-difluor...)
Affinity DataIC50: 13.1nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796608BDBM796608((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 14.2nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796590BDBM796590((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 17.8nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796593BDBM796593((8S,11S)-22-fluoro-10-[1-(4-fluoro-2-methoxy-pheny...)
Affinity DataIC50: 18nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796606BDBM796606((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 18.4nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetStimulator of interferon genes protein [139-379](Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796592BDBM796592((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 21.4nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796591BDBM796591((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 1.00E+4nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796587BDBM796587((8S,11S)-10-[1-(4-fluoro-2-methoxy-phenyl)pyrazolo...)
Affinity DataIC50: 2.00E+4nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 796590BDBM796590((8S,11S)-10-[1-(2,4-difluorophenyl)pyrazolo[3,4-d]...)
Affinity DataIC50: 2.00E+4nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details
US Patent

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