Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 13541
TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802055BDBM802055(US20260108512, Compound 20)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802011BDBM802011(US20260108512, Compound 6)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802056BDBM802056(US20260108512, Compound 21)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802051BDBM802051(US20260108512, Compound 16)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802050BDBM802050(US20260108512, Compound 15)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802053BDBM802053(US20260108512, Compound 18)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801982BDBM801982(US20260108512, Compound 1)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802037BDBM802037(US20260108512, Compound 12)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802038BDBM802038(US20260108512, Compound 13)
Affinity DataIC50: 100nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802025BDBM802025(US20260108512, Compound 8)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802024BDBM802024(US20260108512, Compound 7)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801985BDBM801985(US20260108512, Compound 4)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802054BDBM802054(US20260108512, Compound 19)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801990BDBM801990(US20260108512, Compound 5)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802052BDBM802052(US20260108512, Compound 17)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802032BDBM802032(US20260108512, Compound 11)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802049BDBM802049(US20260108512, Compound 14)
Affinity DataIC50: 300nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802031BDBM802031(US20260108512, Compound 10)
Affinity DataIC50: 5.25E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802030BDBM802030(US20260108512, Compound 9)
Affinity DataIC50: 5.25E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801984BDBM801984(US20260108512, Compound 3)
Affinity DataIC50: 5.25E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-B/Tyrosine-protein kinase Lck(Human)
Hotspot Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 801983BDBM801983(US20260108512, Compound 2)
Affinity DataIC50: 5.25E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent