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Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 13586
TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808523BDBM808523((R)-4-chloro-2,5-dimethyl-N-(3-(2- methylpyrrolidi...)
Affinity DataIC50: 800nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808520BDBM808520(N-(3-(3-cyanomorpholine-4- carbonyl)phenyl)-2,5- d...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808522BDBM808522((R)-4-chloro-2,5-dimethyl-N-(3-(2- methylpiperidin...)
Affinity DataIC50: 2.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808527BDBM808527(3-((4-chloro-2,5- dimethylphenyl)sulfonamido)-N-(1...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808518BDBM808518((R)-2,5-dimethyl-N-(3-(2- methylpiperidine-1- carb...)
Affinity DataIC50: 3.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808515BDBM808515(N-(3-(2-cyanopiperidine-1- carbonyl)phenyl)-2,5- d...)
Affinity DataIC50: 4.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808525BDBM808525(3-((4-chloro-2,5- dimethylphenyl)sulfonamido)-N,N-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808526BDBM808526((R)-4-chloro-N-(3-fluoro-5-(2- methylpyrrolidine-1...)
Affinity DataIC50: 6.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808532BDBM808532(4-chloro-2,5-dimethyl-N-(2-oxoindolin- 5-yl)benzen...)
Affinity DataIC50: 6.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808514BDBM808514((R)-4-chloro-2,5-dimethyl-N-(3-(3- methylmorpholin...)
Affinity DataIC50: 7.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808533BDBM808533(4-chloro-N-(3-(4-cyclopropyl-1-methyl- 1H-imidazol...)
Affinity DataIC50: 7.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808531BDBM808531(4-chloro-2,5-dimethyl-N-(3-(1-methyl- 1H-imidazol-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808521BDBM808521((S)-N-(1-cyclopropylethyl)-3-((2,5- dimethylphenyl...)
Affinity DataIC50: 9.00E+3nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808516BDBM808516(2-methyl-N-(3-(piperidine-1- carbonyl)phenyl)benze...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808528BDBM808528(4-chloro-2,5-dimethyl-N-(3-(thiazol-2- yl)phenyl)b...)
Affinity DataIC50: 1.20E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808519BDBM808519((S)-2,5-dimethyl-N-(3-(2- methylpiperidine-1- carb...)
Affinity DataIC50: 1.20E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808517BDBM808517(N-(cyclopropylmethyl)-3-((2,5- dimethylphenyl)sulf...)
Affinity DataIC50: 4.80E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808530BDBM808530(4-chloro-2,5-dimethyl-N-(3-(1-methyl- 1H-pyrazol-3...)
Affinity DataIC50: 8.10E+4nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808524BDBM808524(N-benzyl-3-((4-chloro-2,5- dimethylphenyl)sulfonam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808529BDBM808529(4-chloro-2,5-dimethyl-N-(3-(oxazol-2- yl)phenyl)be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Human POLγ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent