Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 13592
TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 1nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 1nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 2nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 3nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 5nMAssay Description:Table 29: The assay measures the inhibitory effect of compounds on KRAS mutant protein-protein interactions using the Alpha Screen technology by Perk...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 31nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 44nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 53nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 57nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 60nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 61nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 62nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 69nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 72nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 77nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 78nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 86nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 88nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 95nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 98nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 102nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 123nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 129nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 138nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 139nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 147nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 151nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 153nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 166nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 168nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 179nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 190nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 195nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 215nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 229nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 274nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 280nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 387nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 424nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 446nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 466nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 466nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 472nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 478nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 488nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info
TargetDNA damage-binding protein 1/Protein cereblon(Human)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 489nMAssay Description:Table 26: Test compounds dissolved in DMSO are dispensed onto assay plates (Proxiplate 384 PLUS, white PerkinElmer/revvity; 6008289) using an Access ...More data for this Ligand-Target Pair
Ligand Info











































