Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with all data for entry = 5854
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Glaxo Group

US Patent
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:Recombinant human Syk was express as a His-tagged protein. The activity of Syk was asses using a time-resolved fluorescence resonance entery transfe...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxo Group

US Patent
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)
Affinity DataIC50: >7.90E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant human VEGFR2 (KDR) intracellular domain (including the entire kinase domain) was expressed as a GST-6His-tagged protein. The activity of...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B [2-344]/Inner centromere protein [826-918](Homo sapiens (Human))
Glaxo Group

US Patent
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)
Affinity DataIC50:  2.00E+4nMpH: 8.0 T: 2°CAssay Description:Recombinant human Aurora B (2-344) was expressed as a Flag-6His-Thr-tagged protein. The activity of Aurora B was assessed using a Fluorescence Polar...More data for this Ligand-Target Pair
In DepthDetails US Patent