Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 5857
TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97628BDBM97628(US8470843, 4)
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97626BDBM97626(US8470841, 2)
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97627BDBM97627(US8470843, 3)
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97631BDBM97631(US8470843, 7)
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 1664BDBM1664(US8470843, 13 | US8470843, 14)
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97636BDBM97636(US8470843, 12)
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97634BDBM97634(US8470843, 10)
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97633BDBM97633(US8470843, 9)
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97632BDBM97632(US8470843, 8)
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97635BDBM97635(US8470843, 11)
Affinity DataIC50: 50nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97625BDBM97625(US8470843, 1)
Affinity DataIC50: 60nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97630BDBM97630(US8470843, 6)
Affinity DataIC50: 90nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97629BDBM97629(US8470843, 5)
Affinity DataIC50: 160nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 97638BDBM97638(US8470843, 15)
Affinity DataIC50: 430nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent

TargetHormone-sensitive lipase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 1664BDBM1664(US8470843, 13 | US8470843, 14)
Affinity DataIC50: 740nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
US Patent