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Found 6 Enz. Inhib. hit(s) with all data for entry = 6352
TargetGenome polyprotein(Hepatitis C virus)
Medivir

US Patent
LigandPNGBDBM124107(US8754105, 23)
Affinity DataKi:  0.200nM ΔG°:  -56.3kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Medivir

US Patent
LigandPNGBDBM124112(US8754105, 25)
Affinity DataKi:  2.40nM ΔG°:  -50.0kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Medivir

US Patent
LigandPNGBDBM124111(US8754105, 24)
Affinity DataKi:  40nM ΔG°:  -42.9kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Medivir

US Patent
LigandPNGBDBM124110(US8754105, 17)
Affinity DataKi:  43nM ΔG°:  -42.8kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Medivir

US Patent
LigandPNGBDBM124109(US8754105, 16)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.8kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus)
Medivir

US Patent
LigandPNGBDBM124108(US8754105, 22)
Affinity DataKi:  1.07E+3nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:The aim of this in vitro assay was to measure the inhibition of HCV NS3/4A protease complexes by the compounds of the present invention. This assay p...More data for this Ligand-Target Pair
In DepthDetails US Patent