Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 6458
TargetRho-associated protein kinase 2(Human)
University of Michigan

US Patent
LigandPNGBDBM130375(US8815845, 5)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 uL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 [uM KEAKEKRQEQIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
University of Michigan

US Patent
LigandPNGBDBM130374(US8815845, 4)
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 uL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 [uM KEAKEKRQEQIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
University of Michigan

US Patent
LigandPNGBDBM130371(US8815845, 1)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 uL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 [uM KEAKEKRQEQIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
University of Michigan

US Patent
LigandPNGBDBM130373(US8815845, 3)
Affinity DataIC50: 2.40E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 uL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 [uM KEAKEKRQEQIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM130375(US8815845, 5)
Affinity DataIC50: 2.80E+3nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM130374(US8815845, 4)
Affinity DataIC50: 5.10E+3nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
University of Michigan

US Patent
LigandPNGBDBM130372(US8815845, 2)
Affinity DataIC50: 7.10E+3nMpH: 7.5 T: 2°CAssay Description:In a final reaction volume of 25 uL, ROCK-II (h, amino acids 11-552) (5-10 mU) was incubated with 50 mM Tris pH 7.5, 0.1 mM EGTA, 30 [uM KEAKEKRQEQIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM130372(US8815845, 2)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM130373(US8815845, 3)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
University of Michigan

US Patent
LigandPNGBDBM130371(US8815845, 1)
Affinity DataIC50: 3.00E+4nMpH: 7.0 T: 2°CAssay Description:In a final reaction volume of 25 μL, ROCK-I (h, amino acids 17-535) (5-10 mU) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 μM KEAKE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent