Compile Data Set for Download or QSAR
Report error Found 184 Enz. Inhib. hit(s) with all data for entry = 6507
TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134445(US8846658, 164)
Affinity DataIC50: 1nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134448(US8846658, 167)
Affinity DataIC50: 3nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134463(US8846658, 182)
Affinity DataIC50: 4nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM18751(US8846658, 92 | US8846658, 93)
Affinity DataIC50: 5nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134399(US8846658, 114)
Affinity DataIC50: 6nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM19476(US8846658, 44 | US8846658, 115)
Affinity DataIC50: 6nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134446(US8846658, 165)
Affinity DataIC50: 8nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM18751(US8846658, 92 | US8846658, 93)
Affinity DataIC50: 8nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134434(US8846658, 153)
Affinity DataIC50: 8nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134453(US8846658, 172)
Affinity DataIC50: 9nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134357(US8846658, 69)
Affinity DataIC50: 9nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM50012653(CHEMBL3261067)
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134402(US8846658, 119)
Affinity DataIC50: 10nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134356(US8846658, 68)
Affinity DataIC50: 11nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134441(US8846658, 160)
Affinity DataIC50: 12nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134450(US8846658, 169)
Affinity DataIC50: 12nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134401(US8846658, 118)
Affinity DataIC50: 14nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134378(US8846658, 91)
Affinity DataIC50: 15nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM22021(US8846658, 45 | US8846658, 116)
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134359(US8846658, 71)
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134456(US8846658, 175)
Affinity DataIC50: 16nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM23140(US8846658, 144 | US8846658, 147)
Affinity DataIC50: 17nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134383(US8846658, 97)
Affinity DataIC50: 18nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134400(US8846658, 117)
Affinity DataIC50: 18nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134457(US8846658, 176)
Affinity DataIC50: 18nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM22021(US8846658, 45 | US8846658, 116)
Affinity DataIC50: 18nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134439(US8846658, 158)
Affinity DataIC50: 18nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM19476(US8846658, 44 | US8846658, 115)
Affinity DataIC50: 19nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134354(US8846658, 66)
Affinity DataIC50: 20nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134380(US8846658, 94)
Affinity DataIC50: 22nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134397(US8846658, 111)
Affinity DataIC50: 25nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134407(US8846658, 124)
Affinity DataIC50: 25nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134360(US8846658, 73)
Affinity DataIC50: 26nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134372(US8846658, 85)
Affinity DataIC50: 26nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134382(US8846658, 96)
Affinity DataIC50: 27nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134394(US8846658, 108)
Affinity DataIC50: 28nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134458(US8846658, 177)
Affinity DataIC50: 29nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134387(US8846658, 101)
Affinity DataIC50: 30nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134420(US8846658, 137)
Affinity DataIC50: 30nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134375(US8846658, 88)
Affinity DataIC50: 33nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134424(US8846658, 141)
Affinity DataIC50: 33nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134437(US8846658, 156)
Affinity DataIC50: 34nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134386(US8846658, 100)
Affinity DataIC50: 34nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134358(US8846658, 70)
Affinity DataIC50: 34nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134404(US8846658, 121)
Affinity DataIC50: 36nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134365(US8846658, 78)
Affinity DataIC50: 38nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134377(US8846658, 90)
Affinity DataIC50: 39nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134352(US8846658, 64)
Affinity DataIC50: 40nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM50012654(CHEMBL3261074)
Affinity DataIC50: 42nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Novartis

US Patent
LigandPNGBDBM134421(US8846658, 138)
Affinity DataIC50: 42nMpH: 4.5 T: 2°CAssay Description:Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2015
Entry Details
US Patent

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