Compile Data Set for Download or QSAR
Report error Found 170 Enz. Inhib. hit(s) with all data for entry = 6524
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 30645BDBM30645(US8853193, 32-28)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136194BDBM136194(US8853193, 23-3)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98036BDBM98036(US8486953, 19)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136277BDBM136277(US8853193, 32.7)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136193BDBM136193(US8853193, 23-2)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136283BDBM136283(US8853193, 32-44)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 98040BDBM98040(US8486953, 53)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136200BDBM136200(US8853193, 23-9)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136201BDBM136201(US8853193, 23-10)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136202BDBM136202(US8853193, 24)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136262BDBM136262(US8853193, 53)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 30642BDBM30642(US8853193, 32-27)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 30641BDBM30641(US8853193, 32-26)
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136258BDBM136258(US8853193, 49)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136275BDBM136275(US8853193, 32-5)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136195BDBM136195(US8853193, 23-4)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136175BDBM136175(US8853193, 16-2)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 30636BDBM30636(US8853193, 32-21)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 31312BDBM31312(US8853193, 32-37)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136199BDBM136199(US8853193, 23-8)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136260BDBM136260(US8853193, 51)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136197BDBM136197(US8853193, 23-6)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136185BDBM136185(US8853193, 21-3)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136284BDBM136284(US8853193, 32-45)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136219BDBM136219(US8853193, 31-5)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136263BDBM136263(US8853193, 54)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136188BDBM136188(US8853193, 21-6)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136227BDBM136227(US8853193, 35)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136257BDBM136257(US8853193, 48)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136282BDBM136282(US8853193, 32-43)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136203BDBM136203(US8853193, 25)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136281BDBM136281(US8853193, 32-12)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 32187BDBM32187(US8853193, 32-42)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136274BDBM136274(US8853193, 32-4)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136259BDBM136259(US8853193, 50)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136220BDBM136220(US8853193, 31-6)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 31093BDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136196BDBM136196(US8853193, 23-5)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136278BDBM136278(US8853193, 32-9)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 30638BDBM30638(US8853193, 32-25 | US8853193, 32-23)
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136163BDBM136163(US8853193, 7)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136247BDBM136247(US8853193, 36-19)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136280BDBM136280(US8853193, 32-11)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136226BDBM136226(US8853193, 34-4)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136184BDBM136184(US8853193, 21-2)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136224BDBM136224(US8853193, 33-4)
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 30632BDBM30632(US8853193, 32-17)
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136272BDBM136272(US8853193, 63)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136198BDBM136198(US8853193, 23-7)
Affinity DataIC50: 17nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 136156BDBM136156(US8853193, 3-3)
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:Inhibition of kinase activity of Mnk1 and Mnk2a was assessed with the same assay system, using pre-activated GST-Mnk1 or GST-Mnk2a, respectively. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
US Patent

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