Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 6821
TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152988(US8993614, 53)
Affinity DataIC50: 3.40nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152971(US8993614, 36 | BDBM152973)
Affinity DataIC50: 4.21nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152989(US8993614, 54)
Affinity DataIC50: 4.21nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152966(US8993614, 30)
Affinity DataIC50: 4.30nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152963(US8993614, 24)
Affinity DataIC50: 4.39nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152975(US8993614, 40)
Affinity DataIC50: 4.44nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152980(US8993614, 45 | BDBM152981 | BDBM152982)
Affinity DataIC50: 4.63nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152990(US8993614, 55)
Affinity DataIC50: 4.75nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152979(US8993614, 44)
Affinity DataIC50: 4.86nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152974(US8993614, 39)
Affinity DataIC50: 5.06nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152977(US8993614, 42 | BDBM152978)
Affinity DataIC50: 5.09nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152986(US8993614, 51)
Affinity DataIC50: 5.14nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152976(US8993614, 41)
Affinity DataIC50: 5.18nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152970(US8993614, 35)
Affinity DataIC50: 5.25nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152977(US8993614, 42 | BDBM152978)
Affinity DataIC50: 5.69nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152964(US8993614, 26)
Affinity DataIC50: 5.82nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152959(US8993614, 20)
Affinity DataIC50: 5.84nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152983(US8993614, 48)
Affinity DataIC50: 6.96nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152961(US8993614, 22)
Affinity DataIC50: 7.13nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152972(US8993614, 37)
Affinity DataIC50: 7.14nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152965(US8993614, 28)
Affinity DataIC50: 8.19nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152968(US8993614, 33)
Affinity DataIC50: 8.22nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152969(US8993614, 34)
Affinity DataIC50: 9.09nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152950(US8993614, 11A)
Affinity DataIC50: 10.1nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152944(US8993614, 5)
Affinity DataIC50: 10.4nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152941(US8993614, 2)
Affinity DataIC50: 10.8nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152962(US8993614, 23)
Affinity DataIC50: 11nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152956(US8993614, 17)
Affinity DataIC50: 11.7nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152953(US8993614, 14)
Affinity DataIC50: 12nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152954(US8993614, 15)
Affinity DataIC50: 12.8nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152957(US8993614, 18)
Affinity DataIC50: 13.1nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152955(US8993614, 16)
Affinity DataIC50: 13.4nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152952(US8993614, 13)
Affinity DataIC50: 14.2nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152945(US8993614, 6)
Affinity DataIC50: 14.5nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152942(US8993614, 3)
Affinity DataIC50: 16.3nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152943(US8993614, 4)
Affinity DataIC50: 18.7nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152991(US8993614, 11B)
Affinity DataIC50: 19.4nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152971(US8993614, 36 | BDBM152973)
Affinity DataIC50: 20.2nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152951(US8993614, 12)
Affinity DataIC50: 23.8nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152985(US8993614, 50)
Affinity DataIC50: 26.5nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152987(US8993614, 52)
Affinity DataIC50: 26.7nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152940(US8993614, 1)
Affinity DataIC50: 29.6nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152980(US8993614, 45 | BDBM152981 | BDBM152982)
Affinity DataIC50: 30.3nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152980(US8993614, 45 | BDBM152981 | BDBM152982)
Affinity DataIC50: 40.8nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152960(US8993614, 21)
Affinity DataIC50: 43.5nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152946(US8993614, 7)
Affinity DataIC50: 45nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152958(US8993614, 19)
Affinity DataIC50: 51.4nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152949(US8993614, 10)
Affinity DataIC50: 53.6nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152947(US8993614, 8)
Affinity DataIC50: 53.6nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM152984(US8993614, 49)
Affinity DataIC50: 80.1nMAssay Description:The ability of the compounds to inhibit the interaction between p53 and MDM2 proteins was measured by an HTRF (homogeneous time-resolved fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2015
Entry Details
US Patent

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