Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 7238
TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182852(US9149492, Compound 1D | US12419847, Compound 1D)
Affinity DataIC50: 3.20nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182851(US9149492, Compound 1C | US12419847, Compound 1C)
Affinity DataIC50: 3.60nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182849(US9149492, Compound 1A | US12419847, Compound 1A)
Affinity DataIC50: 4.20nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182850(US9149492, Compound 1B | US12419847, Compound 1B)
Affinity DataIC50: 10.3nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182848(US9149492, Eflucimibe (F12511) | US12419847, Compo...)
Affinity DataIC50: 39nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182848(US9149492, Eflucimibe (F12511) | US12419847, Compo...)
Affinity DataIC50: 110nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182849(US9149492, Compound 1A | US12419847, Compound 1A)
Affinity DataIC50: 275nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182847(US9149492, K-604 | US12419847, Compound K-604)
Affinity DataIC50: 450nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182851(US9149492, Compound 1C | US12419847, Compound 1C)
Affinity DataIC50: 530nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182852(US9149492, Compound 1D | US12419847, Compound 1D)
Affinity DataIC50: 600nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I | US1241...)
Affinity DataIC50: 600nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III | US12...)
Affinity DataIC50: 900nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182850(US9149492, Compound 1B | US12419847, Compound 1B)
Affinity DataIC50: 1.50E+3nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360305(CHEMBL409855 | US9149492, Beauveriolide III | US12...)
Affinity DataIC50: 2.00E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I | US1241...)
Affinity DataIC50: 2.00E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182854(US9149492, 14)
Affinity DataIC50: 2.30E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182853(US9149492, 13)
Affinity DataIC50: 2.40E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM182855(US9149492, 16)
Affinity DataIC50: 3.90E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182853(US9149492, 13)
Affinity DataIC50: 5.30E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM50371698(CHEMBL408322 | US9149492, 1 | US12419847, Compound...)
Affinity DataIC50: 6.10E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 1(Human)
Dartmouth College

US Patent
LigandPNGBDBM50371699(CHEMBL270041 | US9149492, 2 | US12419847, Compound...)
Affinity DataIC50: 6.50E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182854(US9149492, 14)
Affinity DataIC50: 7.50E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182855(US9149492, 16)
Affinity DataIC50: 9.70E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM182847(US9149492, K-604 | US12419847, Compound K-604)
Affinity DataIC50: 1.03E+5nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM50371698(CHEMBL408322 | US9149492, 1 | US12419847, Compound...)
Affinity DataIC50: 2.30E+5nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent

TargetSterol O-acyltransferase 2(Human)
Dartmouth College

US Patent
LigandPNGBDBM50371699(CHEMBL270041 | US9149492, 2 | US12419847, Compound...)
Affinity DataIC50: 4.14E+5nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent