Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 7520
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi:  4.10nM ΔG°:  -47.9kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi:  4.30nM ΔG°:  -47.8kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi:  23.1nM ΔG°:  -43.6kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199179(US9217012, 8)
Affinity DataIC50: 26nMpH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi:  34nM ΔG°:  -42.6kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199179(US9217012, 8)
Affinity DataIC50: 87nMpH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199178(US9217012, 6)
Affinity DataIC50: 160nMpH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199178(US9217012, 6)
Affinity DataKi:  700nM ΔG°:  -35.1kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetDual specificity protein phosphatase 22(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetDual specificity protein phosphatase 3(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase F(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetSerine/threonine-protein phosphatase 2A activator(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetDual specificity protein phosphatase CDC14A(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199180(US9217012, 10)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199177(US9217012, 4)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Indiana University Research and Technology

US Patent
LigandPNGBDBM199177(US9217012, 4)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in DMG buffer (50 mM DMG, pH 7.0, 1 mM EDTA, 150 mM NaCl, 2 mM DTT, 0.1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2016
Entry Details
US Patent