Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 7496
TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197986(US9221767, 58 | US9926282, Example 58)
Affinity DataIC50: 0.300nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197982(US9221767, 33 | US9926282, Example 33)
Affinity DataIC50: 1.20nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197990(US9221767, 76 | US9926282, Example 77)
Affinity DataIC50: 1.20nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197987(US9221767, 61)
Affinity DataIC50: 2.10nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197988(US9221767, 67 | US9926282, Example 66)
Affinity DataIC50: 14nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197979(US9221767, 10 | US9926282, Example 10)
Affinity DataIC50: 17nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197990(US9221767, 76 | US9926282, Example 77)
Affinity DataIC50: 20nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197982(US9221767, 33 | US9926282, Example 33)
Affinity DataIC50: 23nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197978(US9221767, 2 | US9926282, Example 2)
Affinity DataIC50: 30nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197986(US9221767, 58 | US9926282, Example 58)
Affinity DataIC50: 35nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197984(US9221767, 48 | US9926282, Example 48)
Affinity DataIC50: 39nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197987(US9221767, 61)
Affinity DataIC50: 49nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197988(US9221767, 67 | US9926282, Example 66)
Affinity DataIC50: 175nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197985(US9221767, 52 | US9926282, Example 52)
Affinity DataIC50: 225nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197985(US9221767, 52 | US9926282, Example 52)
Affinity DataIC50: 544nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197983(US9221767, 34 | US9926282, Example 34)
Affinity DataIC50: 553nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197984(US9221767, 48 | US9926282, Example 48)
Affinity DataIC50: 670nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197978(US9221767, 2 | US9926282, Example 2)
Affinity DataIC50: 679nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197979(US9221767, 10 | US9926282, Example 10)
Affinity DataIC50: 729nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197989(US9221767, 69)
Affinity DataIC50: 894nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197981(US9221767, 19 | US9926282, Example 19)
Affinity DataIC50: 5.83E+3nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197981(US9221767, 19 | US9926282, Example 19)
Affinity DataIC50: 6.48E+3nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197980(US9221767, 13 | US9926282, Example 13)
Affinity DataIC50: 9.73E+3nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197983(US9221767, 34 | US9926282, Example 34)
Affinity DataIC50: 1.19E+4nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197980(US9221767, 13 | US9926282, Example 13)
Affinity DataIC50: 1.62E+4nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM197989(US9221767, 69)
Affinity DataIC50: 5.00E+4nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details
US Patent