Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 7597
TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205241(US9249123, 102)
Affinity DataIC50: 11.5nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205242(BDBM205248 | US9249123, 104)
Affinity DataIC50: 24.7nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205243(US9249123, 127)
Affinity DataIC50: 29.4nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205246(US9249123, 130)
Affinity DataIC50: 33.7nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205240(US9249123, 101)
Affinity DataIC50: 36.4nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205247(US9249123, 131)
Affinity DataIC50: 47.4nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205242(BDBM205248 | US9249123, 104)
Affinity DataIC50: 95nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Genentech

US Patent
LigandPNGBDBM205249(US9249123, 161)
Affinity DataIC50: 245nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus Bt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details
US Patent