Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 8212
TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236879(US9388171, I-8)
Affinity DataIC50: 0.748nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236882(US9388171, I-24)
Affinity DataIC50: 1.15nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236881(US9388171, I-21)
Affinity DataIC50: 1.86nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236878(US9388171, I-6)
Affinity DataIC50: 2.10nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236886(US9388171, II-15)
Affinity DataIC50: 2.29nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236884(US9388171, II-2)
Affinity DataIC50: 2.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236890(US9388171, II-64)
Affinity DataIC50: 2.68nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236885(US9388171, II-12)
Affinity DataIC50: 2.80nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236880(US9388171, I-11)
Affinity DataIC50: 3.43nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236877(US9388171, I-5)
Affinity DataIC50: 4.04nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236888(US9388171, II-37)
Affinity DataIC50: 4.60nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236890(US9388171, II-64)
Affinity DataIC50: 5.47nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236883(US9388171, I-30)
Affinity DataIC50: 5.95nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236878(US9388171, I-6)
Affinity DataIC50: 5.96nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236889(US9388171, II-46)
Affinity DataIC50: 6.5nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236884(US9388171, II-2)
Affinity DataIC50: 8.5nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236879(US9388171, I-8)
Affinity DataIC50: 9.84nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236886(US9388171, II-15)
Affinity DataIC50: 9.97nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236885(US9388171, II-12)
Affinity DataIC50: 14.8nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236889(US9388171, II-46)
Affinity DataIC50: 15.7nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236877(US9388171, I-5)
Affinity DataIC50: 16.3nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236881(US9388171, I-21)
Affinity DataIC50: 18.7nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetMitogen-activated protein kinase 1 [8-360](Human)
Genetech

US Patent
LigandPNGBDBM236887(US9388171, II-23)
Affinity DataIC50: 20.2nMpH: 7.3Assay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236888(US9388171, II-37)
Affinity DataIC50: 30.4nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236882(US9388171, I-24)
Affinity DataIC50: 37.8nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236887(US9388171, II-23)
Affinity DataIC50: 65.1nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236880(US9388171, I-11)
Affinity DataIC50: 98.9nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Genetech

US Patent
LigandPNGBDBM236883(US9388171, I-30)
Affinity DataIC50: 476nMT: 2°CAssay Description:HepG2 cells were obtained from ATCC and grown in DMEM supplemented with 10% fetal bovine serum. Cells were plated in 96-well plates at 35,000 cells/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent