Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 8331
TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241894BDBM241894(US9416154, 45 | US9416154, 44)
Affinity DataEC50:  2.00E+3nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241885BDBM241885(US9416154, 29)
Affinity DataEC50:  4.55E+3nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241892BDBM241892(US9416154, 42)
Affinity DataEC50:  4.80E+3nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241865BDBM241865(US9416154, 6)
Affinity DataEC50:  9.30E+3nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241866BDBM241866(US9416154, 8)
Affinity DataEC50:  1.30E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241893BDBM241893(US9416154, 43)
Affinity DataEC50:  1.40E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241867BDBM241867(US9416154, 10)
Affinity DataEC50:  1.50E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241891BDBM241891(US9416154, 41)
Affinity DataEC50:  1.80E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241876BDBM241876(US9416154, 19)
Affinity DataEC50: >2.00E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241872BDBM241872(US9416154, 15)
Affinity DataIC50: 2.00E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241881BDBM241881(US9416154, 32)
Affinity DataEC50: >2.00E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241890BDBM241890(US9416154, 40)
Affinity DataEC50:  2.10E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241894BDBM241894(US9416154, 45 | US9416154, 44)
Affinity DataEC50:  2.20E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241861BDBM241861(US9416154, 5)
Affinity DataEC50:  2.30E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241863BDBM241863(US9416154, 2)
Affinity DataEC50:  3.30E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241868BDBM241868(US9416154, 11)
Affinity DataEC50:  3.70E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241869BDBM241869(US9416154, 12)
Affinity DataEC50:  3.90E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241899BDBM241899(US9416154, 37)
Affinity DataIC50: 4.00E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241870BDBM241870(US9416154, 13)
Affinity DataEC50:  5.80E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241859BDBM241859(US9416154, 1)
Affinity DataEC50:  6.10E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241898BDBM241898(US9416154, 36)
Affinity DataIC50: 6.50E+4nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241889BDBM241889(US9416154, 39)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241864BDBM241864(US9416154, 4)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241887BDBM241887(US9416154, 35)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241888BDBM241888(US9416154, 38)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241860BDBM241860(US9416154, 3)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241882BDBM241882(US9416154, 33)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241886BDBM241886(US9416154, 34)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241897BDBM241897(US9416154, 31)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241900BDBM241900(US9416154, 9)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241862BDBM241862(US9416154, 7)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241878BDBM241878(US9416154, 21)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241879BDBM241879(US9416154, 22)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241877BDBM241877(US9416154, 20)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241874BDBM241874(US9416154, 17)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241875BDBM241875(US9416154, 18)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241871BDBM241871(US9416154, 14)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241873BDBM241873(US9416154, 16)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241896BDBM241896(US9416154, 30)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241901BDBM241901(US9416154, 27)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241884BDBM241884(US9416154, 28)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241902BDBM241902(US9416154, 25)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241883BDBM241883(US9416154, 26)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241880BDBM241880(US9416154, 23)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetGenome polyprotein [2420-3010](HCV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 241903BDBM241903(US9416154, 24)
Affinity DataEC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The ability of the nucleoside triphosphate derivatives to inhibit the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent