Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 8334
TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431246(CHEMBL2333062 | US9428465, 32)
Affinity DataIC50: 7nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50: 10nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Human)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM241946(US9428465, 24)
Affinity DataIC50: 14nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Human)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431262(CHEMBL2333042 | US9428465, 5)
Affinity DataIC50: 35nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM241944(US9428465, 16)
Affinity DataIC50: 40nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431262(CHEMBL2333042 | US9428465, 5)
Affinity DataIC50: 51nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431272(CHEMBL2333032 | US9428465, 3)
Affinity DataIC50: 67nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431263(CHEMBL2333041 | US9428465, 8)
Affinity DataIC50: 147nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Human)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50: 155nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431264(CHEMBL2333040 | US9428465, 14)
Affinity DataIC50: 177nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Human)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM241945(US9428465, 23)
Affinity DataIC50: 270nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431269(CHEMBL2333035 | US9428465, 7)
Affinity DataIC50: 420nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431266(CHEMBL2333038 | US9428465, 12)
Affinity DataIC50: 880nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431268(CHEMBL2333036 | US9428465, 9)
Affinity DataIC50: 1.10E+3nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431265(CHEMBL2333039 | US9428465, 13)
Affinity DataIC50: 1.40E+3nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431261(CHEMBL2333044 | US9428465, 11)
Affinity DataIC50: 3.40E+3nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetAcid ceramidase(Rat)
Fondazione Istituto Italiano Di Technologia

US Patent
LigandPNGBDBM50431267(CHEMBL2333037 | US9428465, 10)
Affinity DataIC50: 5.50E+3nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent