Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 8512
TargetBromodomain-containing protein 4 [42-168](Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM254914(US9493483, 402)
Affinity DataIC50: 13nMpH: 7.0 T: 2°CAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM50158612(US9493483, 401 | CHEMBL3787075)
Affinity DataIC50: 14nMpH: 7.0 T: 2°CAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM50158612(US9493483, 401 | CHEMBL3787075)
Affinity DataIC50: 18nMpH: 7.0 T: 2°CAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM254915(US9493483, 403)
Affinity DataIC50: 28nMpH: 7.0 T: 2°CAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM254917(US9493483, 405)
Affinity DataIC50: 175nMpH: 7.0 T: 2°CAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [42-168](Human)
Constellation Pharmaceuticals

US Patent
LigandPNGBDBM254916(US9493483, 404)
Affinity DataIC50: 270nMpH: 7.0 T: 2°CAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2017
Entry Details
Go to US Patent