Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 8562
TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258601(US9493490, Example 13 | US9493490, 6-(4-(aminometh...)
Affinity DataIC50: 0.0550nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258601(US9493490, Example 13 | US9493490, 6-(4-(aminometh...)
Affinity DataIC50: 0.195nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 1.79nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 3.38nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 3.62nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 4.06nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258601(US9493490, Example 13 | US9493490, 6-(4-(aminometh...)
Affinity DataIC50: 4.22nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 5.01nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 5.19nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258596(US9493490, Example 5 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 6.09nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, tert-butyl 2-fl...)
Affinity DataIC50: 7.88nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258596(US9493490, Example 5 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 8.31nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 9.25nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258601(US9493490, Example 13 | US9493490, 6-(4-(aminometh...)
Affinity DataIC50: 10.8nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 10.9nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258597(US9493490, Example 9 | US9493490, F)
Affinity DataIC50: 11.0nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 13.9nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 15.6nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258597(US9493490, Example 9 | US9493490, F)
Affinity DataIC50: 17.2nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258597(US9493490, Example 9 | US9493490, F)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258594(US9493490, Example 3 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258597(US9493490, Example 9 | US9493490, F)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258594(US9493490, Example 3 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258596(US9493490, Example 5 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258596(US9493490, Example 5 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 20nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258596(US9493490, Example 5 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 21.5nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, tert-butyl 2-fl...)
Affinity DataIC50: 25nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258594(US9493490, Example 3 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetProtein kinase C alpha type(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, tert-butyl 2-fl...)
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-adrenergic receptor kinase 1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, tert-butyl 2-fl...)
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258599(US9493490, Example 11 | US9493490, tert-butyl 2-fl...)
Affinity DataIC50: 30nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRAC-alpha serine/threonine-protein kinase(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258597(US9493490, Example 9 | US9493490, F)
Affinity DataIC50: 44.1nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258601(US9493490, Example 13 | US9493490, 6-(4-(aminometh...)
Affinity DataIC50: 47.2nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetcAMP-dependent protein kinase catalytic subunit alpha(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258594(US9493490, Example 3 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 50nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-1(Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258594(US9493490, Example 3 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 50nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258601(US9493490, Example 13 | US9493490, 6-(4-(aminometh...)
Affinity DataIC50: 59.6nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 170nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258598(US9493490, Example 10 | US9493490, G)
Affinity DataIC50: 170nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 216nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258600(US9493490, Example 12 | US9493490, 6-(3-(aminometh...)
Affinity DataIC50: 247nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258596(US9493490, Example 5 | US9493490, 6-(4-(1-aminoeth...)
Affinity DataIC50: 250nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 250nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258592(US9493490, Example 1 | US9493490, 6-(4-(Aminomethy...)
Affinity DataIC50: 250nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258592(US9493490, Example 1 | US9493490, 6-(4-(Aminomethy...)
Affinity DataIC50: 290nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258595(US9493490, Example 4 | US9493490, 6-(4-(aminomethy...)
Affinity DataIC50: 340nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

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