Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 8524
TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255549BDBM255549(US9499534, 1.2)
Affinity DataIC50: 0.959nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255564BDBM255564(US9499534, 2.11)
Affinity DataIC50: 1.11nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255553BDBM255553(US9499534, 1.6)
Affinity DataIC50: 1.29nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255572BDBM255572(US9499534, 2.19)
Affinity DataIC50: 1.29nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255552BDBM255552(US9499534, 1.5)
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255558BDBM255558(US9499534, 2.5)
Affinity DataIC50: 1.56nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255563BDBM255563(US9499534, 2.10)
Affinity DataIC50: 2.38nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255584BDBM255584(US9499534, 3.1)
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255579BDBM255579(US9499534, 2.26)
Affinity DataIC50: 2.68nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255581BDBM255581(US9499534, 2.28)
Affinity DataIC50: 2.75nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255562BDBM255562(US9499534, 2.9)
Affinity DataIC50: 2.78nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255550BDBM255550(US9499534, 1.3)
Affinity DataIC50: 2.95nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255568BDBM255568(US9499534, 2.15)
Affinity DataIC50: 3.22nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255560BDBM255560(US9499534, 2.7)
Affinity DataIC50: 3.68nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255583BDBM255583(US9499534, 2.30)
Affinity DataIC50: 3.94nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255580BDBM255580(US9499534, 2.27)
Affinity DataIC50: 4.06nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255588BDBM255588(US9499534, 1.9)
Affinity DataIC50: 5.10nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255587BDBM255587(US9499534, 1.8)
Affinity DataIC50: 5.77nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255586BDBM255586(US9499534, 1.7)
Affinity DataIC50: 8.48nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255576BDBM255576(US9499534, 2.23)
Affinity DataIC50: 10.1nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255566BDBM255566(US9499534, 2.13)
Affinity DataIC50: 10.2nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255561BDBM255561(US9499534, 2.8)
Affinity DataIC50: 11.7nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255585BDBM255585(US9499534, 3.2)
Affinity DataIC50: 12.4nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255567BDBM255567(US9499534, 2.14)
Affinity DataIC50: 12.9nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255570BDBM255570(US9499534, 2.17)
Affinity DataIC50: 15.3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255582BDBM255582(US9499534, 2.29)
Affinity DataIC50: 16.8nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255574BDBM255574(US9499534, 2.21)
Affinity DataIC50: 17.6nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255559BDBM255559(US9499534, 2.6)
Affinity DataIC50: 20.7nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255577BDBM255577(US9499534, 2.24)
Affinity DataIC50: 24.6nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255589BDBM255589(US9499534, 3.3)
Affinity DataIC50: 34.8nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255578BDBM255578(US9499534, 2.25)
Affinity DataIC50: 35.2nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255565BDBM255565(US9499534, 2.12)
Affinity DataIC50: 35.3nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255571BDBM255571(US9499534, 2.18)
Affinity DataIC50: 37.1nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255575BDBM255575(US9499534, 2.22)
Affinity DataIC50: 46.0nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255554BDBM255554(US9499534, 2.1)
Affinity DataIC50: 48.0nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255557BDBM255557(US9499534, 2.4)
Affinity DataIC50: 63.5nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255573BDBM255573(US9499534, 2.20)
Affinity DataIC50: 70.4nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255551BDBM255551(US9499534, 1.4)
Affinity DataIC50: 77.7nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255556BDBM255556(US9499534, 2.3)
Affinity DataIC50: 149nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255569BDBM255569(US9499534, 2.16)
Affinity DataIC50: 153nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255548BDBM255548(US9499534, 1.1)
Affinity DataIC50: 162nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Tyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 255555BDBM255555(US9499534, 2.2)
Affinity DataIC50: 285nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
US Patent