Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 172
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201005(US9540364, example 15)
Affinity DataEC50:  3nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201004(US9540364, example 14)
Affinity DataEC50:  4nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201001(US9540364, example 13)
Affinity DataEC50:  5nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200996(US9540364, example 8)
Affinity DataEC50:  5nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201006(US9540364, example 16)
Affinity DataEC50:  6nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200995(US9540364, example 7)
Affinity DataEC50:  8nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200992(US9540364, example 3)
Affinity DataEC50:  8nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201007(US9540364, example 17)
Affinity DataEC50:  20nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200997(US9540364, example 9)
Affinity DataEC50:  33nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200998(US9540364, example 10)
Affinity DataEC50:  34nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201008(US9540364, example 18)
Affinity DataEC50:  34nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201011(US9540364, example 21)
Affinity DataEC50:  38nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201010(US9540364, example 20)
Affinity DataEC50:  50nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM201009(US9540364, example 19)
Affinity DataEC50:  67nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200999(US9540364, example 12)
Affinity DataEC50:  76nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200993(US9540364, example 4)
Affinity DataEC50:  104nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200994(US9540364, example 5)
Affinity DataEC50:  209nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200907(US9540364, example 1)
Affinity DataEC50:  216nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM200991(US9540364, example 2)
Affinity DataEC50:  4.29E+3nMpH: 7.3Assay Description:The in vitro AMPK activation assay is performed in a volume of 30 μl in a 384-well plate. Enzyme reactions were assembled in the microtiter plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details
US Patent