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Found 678 Enz. Inhib. hit(s) with all data for entry = 1211
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173376(US10323032, Example 89 | US9096596, 89 | US9604982...)
Affinity DataKi:  1nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173376(US10323032, Example 89 | US9096596, 89 | US9604982...)
Affinity DataKi:  1.20nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173371(US10323032, Example 84 | US9096596, 84 | US9604982...)
Affinity DataKi:  1.90nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173371(US10323032, Example 84 | US9096596, 84 | US9604982...)
Affinity DataKi:  1.90nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173337(US10323032, Example 58 | US9096596, 58 | US9604982...)
Affinity DataKi:  2.80nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173337(US10323032, Example 58 | US9096596, 58 | US9604982...)
Affinity DataKi:  2.80nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173415(US10323032, Example 128 | US9096596, 128 | US96049...)
Affinity DataKi:  3nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173415(US10323032, Example 128 | US9096596, 128 | US96049...)
Affinity DataKi:  3nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173268(US10323032, Example 20 | US9096596, 20 | US9604982...)
Affinity DataKi:  3.5nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173268(US10323032, Example 20 | US9096596, 20 | US9604982...)
Affinity DataKi:  3.5nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173411(US10323032, Example 124 | US9096596, 124 | US96049...)
Affinity DataKi:  3.5nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173411(US10323032, Example 124 | US9096596, 124 | US96049...)
Affinity DataKi:  3.5nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173266(US10323032, Example 18 | US9096596, 18 | US9604982...)
Affinity DataKi:  5nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173266(US10323032, Example 18 | US9096596, 18 | US9604982...)
Affinity DataKi:  5nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173362(US10323032, Example 75 | US9096596, 75 | US9604982...)
Affinity DataKi:  6.30nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173362(US10323032, Example 75 | US9096596, 75 | US9604982...)
Affinity DataKi:  6.30nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM312630((R*)-(2-chloro-3-fluorophenyl)(2,6-dimethyl-4-(1H-...)
Affinity DataKi:  7.40nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173376(US10323032, Example 89 | US9096596, 89 | US9604982...)
Affinity DataKi:  7.70nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173272(US10323032, Example 108 | US9096596, 108 | US90965...)
Affinity DataKi:  7.90nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173365(US10323032, Example 78 | US9096596, 78 | US9604982...)
Affinity DataKi:  7.90nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173272(US10323032, Example 108 | US9096596, 108 | US90965...)
Affinity DataKi:  7.90nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173365(US10323032, Example 78 | US9096596, 78 | US9604982...)
Affinity DataKi:  7.90nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173368(US10323032, Example 81 | US9096596, 81 | US9604982...)
Affinity DataKi:  7.90nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173272(US10323032, Example 108 | US9096596, 108 | US90965...)
Affinity DataKi:  7.90nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173400(US10323032, Example 113 | US9096596, 113 | US96049...)
Affinity DataKi:  7.90nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173400(US10323032, Example 113 | US9096596, 113 | US96049...)
Affinity DataKi:  7.90nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173272(US10323032, Example 108 | US9096596, 108 | US90965...)
Affinity DataKi:  7.90nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173368(US10323032, Example 81 | US9096596, 81 | US9604982...)
Affinity DataKi:  7.90nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173271(US10323032, Example 107 | US9096596, 107 | US90965...)
Affinity DataKi:  9.5nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173271(US10323032, Example 107 | US9096596, 107 | US90965...)
Affinity DataKi:  9.5nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173271(US10323032, Example 107 | US9096596, 107 | US90965...)
Affinity DataKi:  9.5nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173271(US10323032, Example 107 | US9096596, 107 | US90965...)
Affinity DataKi:  9.5nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173310(US10323032, Example 43 | US9096596, 43 | US9604982...)
Affinity DataKi:  10nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173310(US10323032, Example 43 | US9096596, 43 | US9604982...)
Affinity DataKi:  10nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173371(US10323032, Example 84 | US9096596, 84 | US9604982...)
Affinity DataKi:  10nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173371(US10323032, Example 84 | US9096596, 84 | US9604982...)
Affinity DataKi:  10nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173376(US10323032, Example 89 | US9096596, 89 | US9604982...)
Affinity DataKi:  11.5nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173295(US10323032, Example 33 | US9096596, 33 | US9604982...)
Affinity DataKi:  12nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173295(US10323032, Example 33 | US9096596, 33 | US9604982...)
Affinity DataKi:  12nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173406(US10323032, Example 119 | US9096596, 119 | US96049...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173298(US10323032, Example 35 | US9096596, 35 | US9604982...)
Affinity DataKi:  12.6nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173349(US10323032, Example 67 | US9096596, 67 | US9604982...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173353(US10323032, Example 71 | US9096596, 71 | US9604982...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173396(US10323032, Example 109 | US9096596, 109 | US96049...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173405(US10323032, Example 118 | US9096596, 118 | US96049...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173406(US10323032, Example 119 | US9096596, 119 | US96049...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173298(US10323032, Example 35 | US9096596, 35 | US9604982...)
Affinity DataKi:  12.6nMAssay Description:1321N1 cells expressing the recombinant human or rat P2X7 channel was cultured in HyQ DME/(HyClone/Dulbecco's Modified Eagle Medium) high glucose...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173349(US10323032, Example 67 | US9096596, 67 | US9604982...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173405(US10323032, Example 118 | US9096596, 118 | US96049...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM173396(US10323032, Example 109 | US9096596, 109 | US96049...)
Affinity DataKi:  12.6nMAssay Description:Human or rat P2X7-1321N1 cells were collected and frozen @ −80° C. On the day of the experiment, cell membrane preparations were made according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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