Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 1343
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317549(US9624188, 30 | 3-(3-(3-(2,4- difluorophenyl)ureid...)
Affinity DataIC50: 0.700nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317558(US9624188, 49 | racemic)
Affinity DataIC50: 1nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317548(US9624188, 13 | racemic)
Affinity DataIC50: 3nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317556(US9624188, 45 | (r)-3-(3-(2-(4-cyanophenyl)acetami...)
Affinity DataIC50: 5nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317557(US9624188, 46 | 3-(4-(diisobutylamino)-3-(3-(3-(tr...)
Affinity DataIC50: 7nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317550(US9624188, 37 | (r)-3-(4-(diisobutylamino)-3-(3-(p...)
Affinity DataIC50: 11nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317554(US9624188, 43 | (s)-3-(4-(diisobutylamino)-3-(3-(p...)
Affinity DataIC50: 17nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317553(US9624188, 40 | (r)-3-(4-(diisobutylamino)-3-(3-(2...)
Affinity DataIC50: 22nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317551(US9624188, 38 | (s)-3-(4-(diisobutylamino)-3-(3-(p...)
Affinity DataIC50: 29nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317555(US9624188, 44 | (s)-3-(4-(diisobutylamino)-3-(3-(5...)
Affinity DataIC50: 87nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317552(US9624188, 39 | (s)-3-(4-(diisobutylamino)-3-(3-(2...)
Affinity DataIC50: 169nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM317547(US9624188, 2 | 2-(3-(4-(diisobutylamino)-3-(3-(p-t...)
Affinity DataIC50: 205nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent